A 83-01

Citations are publications that use Bio-Techne products. Selected citations for A 83-01 include:

• Jeong et al. (2023) ERdj5 protects goblet cells from endoplasmic reticulum stress-mediated apoptosis under inflammatory conditions Exp Mol Med. 2023;
  PMID: 36759578
• He et al. (2022) Optimized human intestinal organoid model reveals interleukin-22-dependency of paneth cell formation. Cell Stem Cell. 29:1333
  PMID: 36002022
• Han et al. (2022) FOXA2 drives lineage plasticity and KIT pathway activation in neuroendocrine prostate cancer. Cancer Cell. 40:1306
  PMID: 36332622
• Chen et al. (2021) A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells. Nat.Methods. 18:528
  PMID: 33941937
• Duan et al. (2021) An airway organoid-based screen identifies a role for the HIF1α-glycolysis axis in SARS-CoV-2 infection. Cell Rep.. 37:109920
  PMID: 34731648
• Tristan et al. (2021) Robotic high-throughput biomanufacturing and functional differentiation of human pluripotent stem cells. Stem Cell Rep. 16:3076
  PMID: 34861164
• Raghavan et al. (2021) Microenvironment drives cell state, plasticity, and drug response in pancreatic cancer. Cell. 184:6119
  PMID: 34890551
• Kazi et al. (2021) Global phosphoproteomics reveal CDK suppression as a vulnerability to KRas addiction in pancreatic cancer. Clin Cancer Res. 27:4012
  PMID: 33879459
• Post et al. (2020) Snake venom gland organoids. Cell. 180:233
  PMID: 31978343
• Stanifer et al. (2020) Critical Role of Type III Interferon in Controlling SARS-CoV-2 Infection in Human Intestinal Epithelial Cells Cell Rep. 32:107863
  PMID: 32610043
• Kanitz et al. (2019) Conserved regulation of RNA processing in somatic cell reprogramming. BMC Genomics. 20:100
  PMID: 30704403
• Muraoka et al. (2019) Role of cyclooxygenase-2-mediated prostaglandin E2-prostaglandin E receptor 4 signaling in cardiac reprogramming. Nat Commun. 10:674
  PMID: 30787297
• Willigen et al. (2019) Folding-function relationship of the most common cystic fibrosis-causing CFTR conductance mutants. Life Sci Alliance. 2
  PMID: 30659068
• Rostovskaya et al. (2019) Capacitation of human na�ve pluripotent stem cells for multi-lineage differentiation. Development. 146
  PMID: 30944104
• Peterson et al. (2019) Activating a Reserve Neural Stem Cell Population In Vitro Enables Engraftment and Multipotency after Transplantation. Stem Cell Reports. 12:680
  PMID: 30930245
• Saito et al. (2019) Establishment of Patient-Derived Organoids and Drug Screening for Biliary Tract Carcinoma. Cell Rep. 27:1265
  PMID: 31018139
• Mazzucchelli et al. (2019) Establishment and Morphological Characterization of Patient-Derived Organoids from Breast Cancer. Biol Proced Online. 21:12
  PMID: 31223292
• Lindesmith et al. (2019) Sera Antibody Repertoire Analyses Reveal Mechanisms of Broad and Pandemic Strain Neutralizing Responses after Human Norovirus Vaccination. Immunity. 50:1530
  PMID: 31216462
• Ranganathan et al. (2019) Evaluating Shigella flexneri Pathogenesis in the Human Enteroid Model. Infect Immun. 87
  PMID: 30642900
• Wosen et al. (2019) Human Intestinal Enteroids Model MHC-II in the Gut Epithelium. Front Immunol. 10:1970
  PMID: 31481960
• Filippini et al. (2019) Immunoevolution of mouse pancreatic organoid isografts from preinvasive to metastatic disease. Sci Rep. 9:12286
  PMID: 31439856
• Tanigawa et al. (2019) Activin Is Superior to BMP7 for Efficient Maintenance of Human iPSC-Derived Nephron Progenitors. Stem Cell Reports. 13:322
  PMID: 31378669
• Crowell et al. (2019) Expansion of Luminal Progenitor Cells in the Aging Mouse and Human Prostate. Cell Rep. 28:1499
  PMID: 31390564
• Jee et al. (2019) Development of Collagen-Based 3D Matrix for Gastrointestinal Tract-Derived Organoid Culture. Stem Cells Int. 2019:8472712
  PMID: 31312220
• Berkers et al. (2019) Rectal Organoids Enable Personalized Treatment of Cystic Fibrosis. Cell Rep. 26:1701
  PMID: 30759382
• Chen et al. (2019) Chemically Defined Neural Conversion of Human Pluripotent Stem Cells Methods Mol.Biol.. 1919:59
  PMID: 30656621
• Liu et al. (2018) CRISPR-based chromatin remodeling of the endogenous Oct4 or Sox2 locus enables reprogramming to pluripotency. Cell Stem Cell.. 22:252
  PMID: 29358044
• Kashfi et al. (2018) Morphological alterations of cultured human colorectal matched tumour and healthy organoids. Oncotarget. 9:10572
  PMID: 29535828
• Tata et al. (2018) Myoepithelial Cells of Submucosal Glands Can Function as Reserve Stem Cells to Regenerate Airways after Injury. Cell Stem Cell. 22:668
  PMID: 29656943
• Levardon et al. (2018) Expansion of Airway Basal Cells and Generation of Polarized Epithelium. Bio Protoc. 8
  PMID: 30009215
• Yip et al. (2018) Colon organoid formation and cryptogenesis are stimulated by growth factors secreted from myofibroblasts. PLoS One. 13:e0199412
  PMID: 29928021
• Yakoub and Sadek (2018) Development and Characterization of Human Cerebral Organoids: An Optimized Protocol. Cell Transplant. 27:393
  PMID: 29749250
• Roper et al. (2018) Colonoscopy-based colorectal cancer modeling in mice with CRISPR-Cas9 genome editing and organoid transplantation. Nat Protoc. 13:217
  PMID: 29300388
• Biffi et al. (2018) IL-1-induced JAK/STAT signaling is antagonized by TGF-beta to shape CAF heterogeneity in pancreatic ductal adenocarcinoma. Cancer Discov. 2018;
  PMID: 30366930
• Sheng et al. (2018) A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation. Nat Commun. 9:4047
  PMID: 30279449
• Bayrer et al. (2018) LRH-1 mitigates intestinal inflammatory disease by maintaining epithelial homeostasis and cell survival. Nat Commun. 9:4055
  PMID: 30305617
• Li et al. (2018) COX-2-PGE2 Signaling Impairs Intestinal Epithelial Regeneration and Associates with TNF Inhibitor Responsiveness in Ulcerative Colitis. EBioMedicine. 36:497
  PMID: 30190207
• Barros-Silva et al. (2018) Single-Cell Analysis Identifies LY6D as a Marker Linking Castration-Resistant Prostate Luminal Cells to Prostate Progenitors and Cancer. Cell Rep. 25:3504
  PMID: 30566873
• Peng et al. (2018) Inflammatory Cytokine TNFα Promotes the Long-Term Expansion of Primary Hepatocytes in 3D Culture. Cell. 175:1607
  PMID: 30500539
• Rajamani et al. (2018) Super-Obese Patient-Derived iPSC Hypothalamic Neurons Exhibit Obesogenic Signatures and Hormone Responses. Cell Stem Cell. 22:698
  PMID: 29681516
• Lynch et al. (2018) Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium. Cell Stem Cell. 22:653
  PMID: 29656941
• Genovese (2017) Enhanced Development of Skeletal Myotubes from Porcine Induced Pluripotent Stem Cells. Sci Rep. 7:41833
  PMID: 28165492
• Huang et al. (2017) Zfp281 is essential for mouse epiblast maturation through transcriptional and epigenetic control of Nodal signaling. Elife. 6
  PMID: 29168693
• Mulas et al. (2017) NODAL Secures Pluripotency upon Embryonic Stem Cell Progression from the Ground State. Stem Cell Reports. 9:77
  PMID: 28669603
• Pietz et al. (2017) Immunopathology of childhood celiac disease-Key role of intestinal epithelial cells. PLoS One. 12:e0185025
  PMID: 28934294
• Ma et al. (2017) Organoid culture of human prostate cancer cell lines LNCaP and C4-2B. Am J Clin Exp Urol. 5:25
  PMID: 29181435
• Roper et al. (2017) In vivo genome editing and organoid transplantation models of colorectal cancer and metastasis. Nat Biotechnol. 35:569
  PMID: 28459449
• Ruetz et al. (2017) Constitutively Active SMAD2/3 Are Broad-Scope Potentiators of Transcription-Factor-Mediated Cellular Reprogramming. Cell Stem Cell. 21:791
  PMID: 29174331
• Guo et al. (2017) Epigenetic resetting of human pluripotency. Development. 144:2748
  PMID: 28765214
• Roe et al. (2017) Enhancer Reprogramming Promotes Pancreatic Cancer Metastasis. Cell. 170:875
  PMID: 28757253
• Yang et al. (2017) Establishment of mouse expanded potential stem cells. Nature. 550:393
  PMID: 29019987
• Vermilyea et al. (2017) Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. Stem Cells Dev. 26:1225
  PMID: 28635509
• Zhang et al. (2016) Pharmacological reprogramming of fibroblasts into neural stem cells by signaling-directed transcriptional activation. Cell Stem Cell. 18(653)
  PMID: 27133794
• Mou et al. (2016) Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells Cell: Stem Cell. 19:217
  PMID: 27320041
• Foulke-Abel et al. (2016) Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology. Nat Protoc. 150:638
  PMID: 26677983
• Drost et al. (2016) Organoid culture systems for prostate epithelial and cancer tissue. Proc Natl Acad Sci U S A. 11:347
  PMID: 26797458
• Wang et al. (2016) Anti-tumor activity of SL4 against breast cancer cells: induction of G2/M arrest through modulation of the MAPK-dependent p21 signaling pathway. Sci Rep. 6:36486
  PMID: 27819344
• Zamudio et al. (2016) Inhibition of TGFβ cell signaling for limbal explant culture in serumless, defined xeno-free conditions. Exp Eye Res. 145:48
  PMID: 26554938
• Mousavizadeh et al. (2016) Angiopoietin-like 4 promotes angiogenesis in the tendon and is increased in cyclically loaded tendon fibroblasts. J Physiol. 594:2971
  PMID: 26670924
• Dai et al. (2015) Maintenance and neuronal differentiation of chicken induced pluripotent stem-like cells. Stem Cells Int. 2014:182737
  PMID: 25610469
• Tan et al. (2015) Amnion cell mediated immune modulation following bleo. challenge: controlling the regulatory T cell response. Stem Cell Res Ther. 6:8
  PMID: 25634246
• Zhao et al. (2015) High-efficiency reprogramming of fibroblasts into cardiomyocytes requires suppression of pro-fibrotic signalling. Nat Commun. 6:8243
  PMID: 26354680
• Weeber et al. (2015) Preserved genetic diversity in organoids cultured from biopsies of human colorectal cancer metastases. Hum Mol Genet. 112:13308
  PMID: 26460009
• Mattis et al. (2015) HD iPSC-derived neural progenitors accumulate in culture and are susceptible to BDNF withdrawal due to glutamate toxicity. Exp Cell Res. 24:3257
  PMID: 25740845
• Bras et al. (2015) TGFβ loss activates ADAMTS-1-mediated EGF-dependent invasion in a model of esophageal cell invasion. Nat Genet. 330:29
  PMID: 25064463
• Liao et al. (2015) Targeted disruption of DNMT1, DNMT3A and DNMT3B in human embryonic stem cells. Cell. 47:469
  PMID: 25822089
• Boj et al. (2015) Organoid models of human and mouse ductal pancreatic cancer. Cell. 160:324
  PMID: 25557080
• Huch et al. (2015) Long-term culture of genome-stable bipotent stem cells from adult human liver. Nature. 160:299
  PMID: 25533785
• Tsankov et al. (2015) Transcription factor binding dynamics during human ES cell differentiation. Stem Cell Reports. 518:344
  PMID: 25693565
• Kido et al. (2015) CPM Is a Useful Cell Surface Marker to Isolate Expandable Bi-Potential Liver Progenitor Cells Derived from Human iPS Cells. Inflamm Bowel Dis. 5:508
  PMID: 26365514
• Sibony et al. (2015) Microbial Disruption of Autophagy Alters Expression of the RISC Component AGO2, a Critical Regulator of the miRNA Silencing Pathway. Proc Natl Acad Sci U S A. 21:2778
  PMID: 26332312
• Yang et al. (2015) Heightened potency of human pluripotent stem cell lines created by transient BMP4 exposure. Stem Cell Reports. 112:E2337
  PMID: 25870291
• Nantasanti et al. (2015) Disease Modeling and Gene Therapy of Copper Storage Disease in Canine Hepatic Organoids. Stem Cell Res. 5:895
  PMID: 26455412
• Corritore et al. (2014) β-Cell differentiation of human pancreatic duct-derived cells after in vitro expansion. Cell Cycle. 16:456
  PMID: 25437872
• Li et al. (2014) PMA induces SnoN proteolysis and CD61 expression through an autocrine mechanism. Cell Signal. 26:1369
  PMID: 24637302
• O'Malley et al. (2013) High-resolution analysis with novel cell-surface markers identifies routes to iPS cells. Nature. 499:88
  PMID: 23728301
• Yanagida et al. (2013) An in vitro expansion system for generation of human iPS cell-derived hepatic progenitor-like cells exhibiting a bipotent differentiation potential. PLoS One. 8:e67541
  PMID: 23935837
• Okiyoneda et al. (2013) Mechanism-based corrector combination restores δF508-CFTR folding and function. Nat Chem Biol. 9:444
  PMID: 23666117
• Kearns et al. (2013) Generation of organized anterior foregut epithelia from pluripotent stem cells using small molecules. PLoS One. 11:1003
  PMID: 23917481
• Schwank et al. (2013) Generation of BAC transgenic epithelial organoids. Cell Reprogram. 8:e76871
  PMID: 24204693
• Boilàve et al. (2013) Immunosurveillance against tetraploidization-induced colon tumorigenesis. Proc Natl Acad Sci U S A. 12:473
  PMID: 23324343
• Hirschhorn et al. (2012) Differential regulation of Smad3 and of the type II transforming growth factor-β receptor in mitosis: implications for signaling. PLoS One. 7:e43459
  PMID: 22927969
• Telugu et al. (2011) Porcine induced pluripotent stem cells analogous to naïve and primed embryonic stem cells of the mouse. Int J Dev Biol. 54:1703
  PMID: 21305472
• Kawamata and Ochiya (2010) Generation of genetically modified rats from embryonic stem cells. Nature. 107:14223
  PMID: 20660726

There are no citations that match your criteria.

Customer Images

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• (7)

• Works perfectly

  Name: Toni Johansson
  Species: Human
  Assay Type: In Vitro
  To grow primary basal cells
  

• Works well with liver organoids

  Name: Gautam Kok
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: Liver organoids
  Used in expansion medium for culturing liver organoids
  

• It worked good

  Name: Anonymous
  Species: Mouse
  Assay Type: In Vitro
  Cell Line/Tissue: iPSC
  Reprogramming media comprises of 3 μM CHIR99021 and 0.5 μM A-83-01.
  The cells were then maintained in RM 15 days with fresh media every other day
  PMID: 29681516
  

• For TGFB inhibition

  Name: Anonymous
  Species: Mouse
  Assay Type: In Vitro
  Cell Line/Tissue: Neural Stem Cells
  Cells are treated with 1 mM A83-01 to inhibit canonical TGFB signaling
  PMID: 27133794
  

• Neural Induction Conditions

  Name: Anonymous
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: H9
  2 μM A83–01
  PMID: 30656621
  

• To start reprogramming, cultures were switched to reprogramming medium (ES medium supplemented with 1 mM A83-01)

  Name: Anonymous
  Species: Mouse
  Assay Type: In Vitro
  Cell Line/Tissue: ipsc
  To start reprogramming, cultures were switched to reprogramming medium (ES medium supplemented with 10 mM Parnate, 3 mM Chir99021, 1 mM A83-01, and 10 mM Forskolin)
  PMID: 29358044
  

• good for cell culture

  Name: Anonymous
  Species: Mouse
  Assay Type: In Vivo
  Cell Line/Tissue: ipsc
  add to cell culture to do 3d culture
  PMID: PMID: 29930984 Reference
  

• works great for TGFB inhibition

  Name: Anonymous
  Species: Human
  Assay Type: In Vitro
  used it to grow primary basal cells
  PMID: 27320041

• for growing cells

  Name: Anonymous
  Species: Human
  Assay Type: In Vitro
  used it to grow human airway basal cells

• A 83-01 Inhibit TGFb1-activated Cellular Fibrosis in Human Mϋller Cells

  Name: Ying Yu
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: Mϋller cells
  Human MOI-M1 Mϋller cells seeded in tissue culture (TC)-treated plastic plate (BD). Serum starvation by DMEM medium supplemented with 1% FBS for 24h. Pretreated Human Mϋller cell with A83-01 at 0, 0.25, 0.5, 1 and 2uM for 2h. Then added 0-10 ng/mL TGFb1 for 48h. Picro-Sirius red staining, elution, and OD 540nm measurement for the fibrosis

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