Human/Mouse/Rat SOX2 Antibody Best Seller
Catalog # MAB2018 | R&D Systems, Inc. a Bio-Techne Brand
Key Product Details
Species Reactivity
Applications
Label
Antibody Source
Product Summary for Human/Mouse/Rat SOX2 Antibody
Immunogen
Gly135-Met317
Accession # P48431
Specificity
Clonality
Host
Isotype
Scientific Data Images for Human/Mouse/Rat SOX2 Antibody
E‑Cadherin and SOX2 in BG01V Human Stem Cells.
E-Cadherin and SOX2 were detected in BG01V human embryonic stem cells using 10 µg/mL Goat Anti-Human E-Cadherin Antigen Affinity-purified Polyclonal Antibody (AF648) and 10 µg/mL Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018). Cells were incubated with primary antibodies for 3 hours at room temperature. Cells were stained for E-Cadherin using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and for SOX2 using the NorthernLights 493-conjugated Anti-Mouse Secondary Antibody (green; NL009). Cells were counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.Detection of Human, Mouse, and Rat SOX2 by Western Blot.
Western blot shows lysates of NTera-2 human testicular embryonic carcinoma cell line, F9 mouse teratocarcinoma stem cells, D3 mouse embryonic stem cell line, and rat cortical stem cells. PVDF membrane was probed with 1 µg/mL of Mouse Anti-Human/Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (HAF018). A specific band was detected for SOX2 at approximately 36 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.SOX2 in BG01V Human Embryonic Stem Cells.
SOX2 was detected in immersion fixed BG01V human embryonic stem cells using Mouse Anti-Human/ Mouse/Rat SOX2 Monoclonal Antibody (Catalog # MAB2018) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (yellow; NL007) and counterstained with DAPI (blue). View our protocol for Fluorescent ICC Staining of Cells on Coverslips.Applications for Human/Mouse/Rat SOX2 Antibody
CyTOF-reported
Immunocytochemistry
Sample: Immersion fixed BG01V human embryonic stem cells and immersion fixed NTera‑2 human embryonic carcinoma cells
Immunohistochemistry
Sample: Immersion fixed paraffin-embedded sections of glioblastoma
Intracellular Staining by Flow Cytometry
Sample: NTera‑2 human embryonic carcinoma cell line fixed with Flow Cytometry Fixation Buffer (Catalog # FC004) and permeabilized with Flow Cytometry Permeabilization/Wash Buffer I (Catalog # FC005)
Simple Western
Sample: BG01V human embryonic stem cells
Western Blot
Sample: NTera‑2 human testicular embryonic carcinoma cell line, F9 mouse teratocarcinoma stem cells, D3 mouse embryonic stem cell line, and rat cortical stem cells
Reviewed Applications
Read 13 reviews rated 4.5 using MAB2018 in the following applications:
- Immunocytochemistry/Immunofluorescence (6 Reviews)
- Immunofluorescence (5 Reviews)
- Immunohistochemistry (1 Review)
- Western Blot (1 Review)
Published Applications
Read 183 publications using MAB2018 in the following applications:
Formulation, Preparation and Storage
Purification
Reconstitution
Formulation
Shipping
Stability & Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: SOX2
References
- Graham, V. et al. (2003) Neuron 39:749.
- Avilion, A.A. et al. (2003) Genes Dev. 17:126.
- Kishi, M. et al. (2000) Development 127:791.
- Yuan, H. et al. (1995) Genes Dev. 9:2635.
- Uwanogho, D. et al. (1995) Mech. Dev. 49:23.
- Stevanovic, M. (2003) Mol. Biol. Rep. 30:127.
Long Name
Alternate Names
Entrez Gene IDs
Gene Symbol
UniProt
Product Documents for Human/Mouse/Rat SOX2 Antibody
Product Specific Notices for Human/Mouse/Rat SOX2 Antibody
For research use only
Citations for Human/Mouse/Rat SOX2 Antibody (183)
Citations are publications that use Bio-Techne products. Selected citations for Human/Mouse/Rat SOX2 Antibody include:
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Species: Human
Sample Types: Whole Cells
Applications: ICC,Flow CytometryYin et al. (2023-06-01), Generation of a human induced pluripotent stem cell line (FDCHi010-A) from a patient with Xia-Gibbs syndrome carrying AHDC1 mutation (c.2062C�>�T) Stem cell research
PMID: 37216737 -
Species: Mouse
Sample Types: Cell Lysates
Applications: Western BlotRobertson et al. (2023-05-26), Elevated FOXG1 in glioblastoma stem cells cooperates with Wnt/?-catenin to induce exit from quiescence Cell reports
PMID: 37243590 -
Species: Human
Sample Types: Whole Cells
Applications: ICCTam et al. (2023-05-25), IPSC-Derived Sensory Neurons Directing Fate Commitment of Human BMSC-Derived Schwann Cells: Applications in Traumatic Neural Injuries Cells
PMID: 37296600 -
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICCLuo et al. (2023-05-09), Generation of a homozygous GRIN2A gene knockout human embryonic stem cell line using CRISPR/Cas9 system Stem cell research
PMID: 37182381 -
Species: Human
Sample Types: Transfected Whole Cells
Applications: ICCNM Schottmann et al. (2023-04-12), Generation of induced pluripotent stem cell line (UKWNLi008) derived from a patient carrying a c.1678C>G variant in the transient receptor potential cation channel subfamily A member (TRPA1) gene potentially associated with small fiber neuropathy Stem Cell Research, 2023-069(0):103094.
PMID: 37079968 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryW Feng et al. (2023-02-26), Generation of an induced pluripotent stem cell line from an aortic dissection patient carrying MCTP2/c.2635T�>�G mutation Stem Cell Research, 2023-068(0):103058.
PMID: 36868039 -
Species: Human
Sample Types: Organoid,Whole Cells
Applications: ICC,IHCMF Wells et al. (2023-02-15), Natural variation in gene expression and viral susceptibility revealed by neural progenitor cell villages Cell Stem Cell, 2023-00(0).
PMID: 36796362 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCJ Dougherty et al. (2023-02-02), Identification of therapeutic sensitivities in a spheroid drug combination screen of Neurofibromatosis Type I associated High Grade Gliomas PLoS ONE, 2023-018(2):e0277305.
PMID: 36730269 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCKW Govek et al. (2022-12-06), Developmental trajectories of thalamic progenitors revealed by single-cell transcriptome profiling and Shh perturbation Cell Reports, 2022-141(10):111768.
PMID: 36476860 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotI Berglar et al. (2022-12-03), CHRDL1 Regulates Stemness in Glioma Stem-like Cells Cells, 2022-111(23).
PMID: 36497175 -
Species: Moose
Sample Types: Cell Lysates
Applications: Western BlotZ Xiao et al. (2022-10-21), A TNFR1-UBCH10 axis drives lung squamous cell carcinoma dedifferentiation and metastasis through a cell-autonomous signaling loop Cell Death & Disease, 2022-113(10):885.
PMID: 36270982 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryR Chimienti et al. (2022-09-27), Engineering of immune checkpoints B7-H3 and CD155 enhances immune compatibility of MHC-I-/- iPSCs for beta cell replacement Cell Reports, 2022-040(13):111423.
PMID: 36170817 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCA Lauko et al. (2022-09-13), SerpinB3 drives cancer stem cell survival in glioblastoma Cell Reports, 2022-040(11):111348.
PMID: 36103817 -
Species: Mouse
Sample Types: Whole Cells
Applications: Western BlotM Okada et al. (2022-08-07), Inhibition of the Phospholipase Cepsilon-c-Jun N-Terminal Kinase Axis Suppresses Glioma Stem Cell Properties International Journal of Molecular Sciences, 2022-023(15).
PMID: 35955917 -
Species: Human
Sample Types: Cell Lysates
Applications: Immunoprecipitation,ChIPS Pietrobono et al. (2022-08-07), p38 MAPK-dependent phosphorylation of transcription factor SOX2 promotes an adaptive response to BRAF inhibitors in melanoma cells The Journal of Biological Chemistry, 2022-0298(9):102353.
PMID: 35944584 -
Species: Human
Sample Types: Cell Lysate
Applications: Western BlotV Benedetti et al. (2022-08-03), A SOX2-engineered epigenetic silencer factor represses the glioblastoma genetic program and restrains tumor development Science Advances, 2022-08(31):eabn3986.
PMID: 35921410 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotY Nakagawa-S et al. (2022-07-22), HDAC Class I Inhibitor Domatinostat Preferentially Targets Glioma Stem Cells over Their Differentiated Progeny International Journal of Molecular Sciences, 2022-023(15).
PMID: 35897656 -
Species: Human
Sample Types: Whole Cells
Applications: ICC,Flow CytometryJ Lotila et al. (2022-07-11), Establishment of a human induced pluripotent stem cell line (TAUi008-A) derived from a multiple sclerosis patient Oncogene, 2022-063(0):102865.
PMID: 35843021 -
Species: Human
Sample Types: Whole Cells
Applications: ICCRR Khadim et al. (2022-06-30), Integrating Oxygen and 3D Cell Culture System: A Simple Tool to Elucidate the Cell Fate Decision of hiPSCs International Journal of Molecular Sciences, 2022-023(13).
PMID: 35806277 -
Species: Human
Sample Types: Whole Cells
Applications: ICCY Yoshida et al. (2022-06-27), Changes in the Expression of Smooth Muscle Cell-Related Genes in Human Dermal Sheath Cup Cells Associated with the Treatment Outcome of Autologous Cell-Based Therapy for Male and Female Pattern Hair Loss International Journal of Molecular Sciences, 2022-023(13).
PMID: 35806129 -
Species: Human
Sample Types: Whole Cells
Applications: ICCLJ Flitsch et al. (2022-05-19), Identification of adeno-associated virus variants for gene transfer into human neural cell types by parallel capsid screening Scientific Reports, 2022-012(1):8356.
PMID: 35589936 -
Species: Human
Sample Types: Whole Cells
Applications: ICCM Tisch et al. (2022-04-09), Generation of the human induced pluripotent stem cell line (IBKMOLi002-A) from PBMCs of a patient carrying the heterozygous L271H mutation of the voltage-gated calcium channel subunit Cav1.3-encoding CACNA1D gene Stem Cell Research, 2022-061(0):102784.
PMID: 35453044 -
Species: Human
Sample Types: Whole Cells
Applications: ICC,Flow CytometryC Maranga et al. (2022-03-21), Generation and characterization of induced pluripotent stem cell line (IBBISTi004-A) from an Angelman syndrome patient carrying a class II deletion of the maternal chromosome 15q11.2-q13 Stem Cell Research, 2022-061(0):102757.
PMID: 35339881 -
Species: Human
Sample Types: Whole Cells
Applications: ICCM Breyer et al. (2022-03-14), Generation of the induced pluripotent stem cell line UKWNLi005-A derived from a patient with the GLA mutation c.376A�>�G of unknown pathogenicity in Fabry disease Stem Cell Research, 2022-061(0):102747.
PMID: 35325818 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCB Polat et al. (2022-02-19), Differences in stem cell marker and osteopontin expression in primary and recurrent glioblastoma Cancer Cell International, 2022-022(1):87.
PMID: 35183162 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCA Del Giovan et al. (2022-01-10), Smoothened/AMP-Activated Protein Kinase Signaling in Oligodendroglial Cell Maturation Frontiers in Cellular Neuroscience, 2022-015(0):801704.
PMID: 35082605 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryKG Zyner et al. (2022-01-10), G-quadruplex DNA structures in human stem cells and differentiation Nature Communications, 2022-013(1):142.
PMID: 35013231 -
Species: Human
Sample Types: Whole Cells
Applications: ICCIC Han et al. (2022-01-01), Biocompatibility of Human Induced Pluripotent Stem Cell-Derived Retinal Progenitor Cell Grafts in Immunocompromised Rats Cell Transplantation, 2022-031(0):9636897221104.
PMID: 35758274 -
Species: Human
Sample Types: Organoid
Applications: IHCM Notaras et al. (2021-11-17), Schizophrenia is defined by cell-specific neuropathology and multiple neurodevelopmental mechanisms in patient-derived cerebral organoids Molecular Psychiatry, 2021-10(0).
PMID: 34789849 -
Species: Human,Mouse
Sample Types: Cell Lysates
Applications: Western BlotF Pecori et al. (2021-07-13), Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis Cell Reports, 2021-036(2):109361.
PMID: 34260942 -
Species: Human
Sample Types: Whole Cells
Applications: ICCBM Brooks et al. (2021-06-24), Generation of an induced pluripotent stem cell line (TRNDi031-A) from a patient with Alagille syndrome type 1 carrying a heterozygous p. C312X (c. 936�T�>�A) mutation in JAGGED-1 Stem Cell Research, 2021-054(0):102447.
PMID: 34198154 -
Species: Human
Sample Types: Organoids
Applications: IHCM Notaras et al. (2021-06-22), Neurodevelopmental signatures of narcotic and neuropsychiatric risk factors in 3D human-derived forebrain organoids Molecular Psychiatry, 2021-00(0).
PMID: 34158620 -
Species: Human
Sample Types: Whole Cells
Applications: ICCL Ma et al. (2021-06-18), Human iPSC lines from a Christianson syndrome patient with NHE6 W523X mutation, a biologically-related control, and CRISPR/Cas9 gene-corrected isogenic controls Stem Cell Research, 2021-054(0):102435.
PMID: 34182254 -
Species: Human
Sample Types: Whole Cells
Applications: ICCF Xiong et al. (2021-06-09), RNA m6A modification orchestrates a LINE-1-host interaction that facilitates retrotransposition and contributes to long gene vulnerability Cell Research, 2021-00(0).
PMID: 34108665 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryX Huang et al. (2021-06-07), Generation of an induced pluripotent stem cell line (TRNDi012-B) from Fibrodysplasia Ossificans Progressiva (FOP) patient carrying a heterozygous mutation c. 617G�>�A in the ACVR1 gene Stem Cell Research, 2021-054(0):102424.
PMID: 34139597 -
Species: Human
Sample Types: Whole Cells
Applications: ICCYC Lin et al. (2021-05-31), Interactions between ALS-linked FUS and nucleoporins are associated with defects in the nucleocytoplasmic transport pathway Nature Neuroscience, 2021-00(0).
PMID: 34059832 -
Species: Human
Sample Types: Whole Cells
Applications: ICC,Flow CytometryM Pradhan et al. (2021-05-20), An induced pluripotent stem cell line (NCATS-CL9075) from a patient carrying compound heterozygote mutations, p.R390P and p.L318P, in the NGLY1 gene Stem Cell Research, 2021-054(0):102400.
PMID: 34051448 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryMS Lee et al. (2021-05-19), Comparative evaluation of isogenic mesodermal and ectomesodermal chondrocytes from human iPSCs for cartilage regeneration Science Advances, 2021-07(21).
PMID: 34138734 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryBM Brooks et al. (2021-05-12), Generation of an induced pluripotent stem cell line (TRNDi030-A) from a patient with Farber disease carrying a homozygous p. Y36C (c. 107 A>G) mutation in ASAH1 Stem Cell Research, 2021-053(0):102387.
PMID: 34088014 -
Species: Human
Sample Types: Whole Cells
Applications: ICCW Zhu et al. (2021-04-27), Generation of Alagille syndrome derived induced pluripotent stem cell line carrying heterozygous mutation in the JAGGED-1 gene at splicing site (Chr20: 10,629,709C>A) before exon 11 Stem Cell Research, 2021-053(0):102366.
PMID: 34087995 -
Species: Human
Sample Types: Whole Cells
Applications: ICCTP Silva et al. (2021-04-23), Generation and characterization of induced pluripotent stem cells heterozygous for the Portuguese BRCA2 founder mutation Stem Cell Research, 2021-053(0):102364.
PMID: 34087993 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCMA Khuu et al. (2021-03-16), Stage-dependent effects of intermittent hypoxia influence the outcome of hippocampal adult neurogenesis Scientific Reports, 2021-011(1):6005.
PMID: 33727588 -
Species: Human
Sample Types: Whole Cells
Applications: ICCRB Bressan et al. (2021-02-24), Regional identity of human neural stem cells determines oncogenic responses to histone H3.3 mutants Cell Stem Cell, 2021-00(0).
PMID: 33631116 -
Species: Human
Sample Types: Whole Cells
Applications: ICC,Flow CytometryTP Silva et al. (2021-02-11), Generation and characterization of induced pluripotent stem cells from a family carrying the BRCA1 mutation c.3612delA Stem Cell Research, 2021-052(0):102242.
PMID: 33631522 -
Species: Human
Sample Types: Whole Cells
Applications: ICCV Pasquale et al. (2020-12-11), Profiling and Targeting of Energy and Redox Metabolism in Grade 2 Bladder Cancer Cells with Different Invasiveness Properties Cells, 2020-19(12).
PMID: 33322565 -
Species: Human
Sample Types: Whole Cells
Applications: IHCST Chen et al. (2020-12-01), Insulin-like growth factor 1 partially rescues early developmental defects caused by SHANK2 knockdown in human neurons Neural Regen Res, 2020-115(12):2335-2343.
PMID: 32594058 -
Species: Human
Sample Types: Cell Lysates
Applications: ChIPS Pietrobono et al. (2020-11-17), ST3GAL1 is a target of the SOX2-GLI1 transcriptional complex and promotes melanoma metastasis through AXL Nat Commun, 2020-111(1):5865.
PMID: 33203881 -
Species: Human
Sample Types: Whole Cells
Applications: ICCX Ji et al. (2020-11-17), Generation of an induced pluripotent stem cell line from an Alstr�m Syndrome patient with ALMS1 mutation (c.3902C�>�A, c.6436C�>�T) and a gene correction isogenic iPSC line Stem Cell Res, 2020-149(0):102089.
PMID: 33264725 -
Species: Mouse
Sample Types: Cell Lysates
Applications: Western BlotF Pecori et al. (2020-10-23), Mucin-type O-glycosylation controls pluripotency in mouse embryonic stem cells via Wnt receptor endocytosis J. Cell. Sci., 2020-10(0).
PMID: 32973111 -
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICCX Xu et al. (2020-10-01), Four induced pluripotent stem cell lines (TRNDi021-C, TRNDi023-D, TRNDi024-D and TRNDi025-A) generated from fibroblasts of four healthy individuals Stem Cell Res, 2020-149(0):102011.
PMID: 33038742 -
Species: Human
Sample Types: Whole Cells
Applications: ICCSR Sripathy et al. (2020-09-17), Generation of 10 patient-specific induced pluripotent stem cells (iPSCs) to model Pitt-Hopkins Syndrome Stem Cell Res, 2020-048(0):102001.
PMID: 32971458 -
Species: Human
Sample Types: Complex Sample Type,Whole Tissue
Applications: IHCAA Zalenski et al. (2020-08-18), An interphase pool of KIF11 localizes at the basal bodies of primary cilia and a reduction in KIF11 expression alters cilia dynamics Sci Rep, 2020-010(1):13946.
PMID: 32811879 -
Species: Mouse
Sample Types: Whole Tissue,Whole Cells
Applications: ICC,IHCL Muzio et al. (2020-07-31), Retromer stabilization results in neuroprotection in a model of Amyotrophic Lateral Sclerosis Nat Commun, 2020-011(1):3848.
PMID: 32737286 -
Species: Human
Sample Types: Whole Cells
Applications: ICCG Kaufman et al. (2020-06-26), The self-renewal dental pulp stem cell microtissues challenged by a toxic dental monomer Biosci. Rep., 2020-040(6).
PMID: 32495822 -
M Mehdipour et al. (2020-05-30), Rejuvenation of three germ layers tissues by exchanging old blood plasma with saline-albumin Aging (Albany NY), 2020-012(10):8790-8819.
PMID: 32474458 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotI Gomes et al. (2020-05-12), Expression of receptor activator of NFkB (RANK) drives stemness and resistance to therapy in ER+HER2- breast cancer Oncotarget, 2020-011(19):1714-1728.
PMID: 32477461 -
Species: Human
Applications: IFN Micali et al. (2020-05-05), Variation of Human Neural Stem Cells Generating Organizer States In�Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates Cell Rep, 2020-031(5):107599.
PMID: 32375049 -
Species: Pan troglodytes (Chimpanzee)
Sample Types: Whole Cells
Applications: ICCR Kitajima et al. (2020-02-28), Modeling of early neural development in vitro by direct neurosphere formation culture of chimpanzee induced pluripotent stem cells Stem Cell Res, 2020-044(0):101749.
PMID: 32151953 -
Species: Human
Sample Types: Whole Cells
Applications: ICCR Li et al. (2020-02-19), An induced pluripotent stem cell line (TRNDi001-D) from a Niemann-Pick disease type C1 (NPC1) patient carrying a homozygous p. I1061T (c. 3182T>C) mutation in the NPC1 gene Stem Cell Res, 2020-044(0):101737.
PMID: 32114296 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCL Su et al. (2020-02-03), PRDM16 orchestrates angiogenesis via neural differentiation in the developing brain Cell Death Differ., 2020-00(0).
PMID: 32015502 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCH Hengel et al. (2020-01-30), Loss-of-function mutations in UDP-Glucose 6-Dehydrogenase cause recessive developmental epileptic encephalopathy Nat Commun, 2020-011(1):595.
PMID: 32001716 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCT Hyvärinen et al. (2019-11-20), Functional characterization of human pluripotent stem cell-derived cortical networks differentiated on laminin-521 substrate: comparison to rat cortical cultures Sci Rep, 2019-19(1):17125.
PMID: 31748598 -
Species: Human
Sample Types: Whole Cells
Applications: ICCM Mura et al. (2019-11-20), Generation of the human induced pluripotent stem cell (hiPSC) line PSMi006-A from a patient affected by an autosomal recessive form of long QT syndrome type 1 Stem Cell Res, 2019-142(0):101658.
PMID: 31785541 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-PE Grall et al. (2019-10-24), Severe head dysgenesis resulting from imbalance between anterior and posterior ontogenetic programs Cell Death Dis, 2019-110(11):812.
PMID: 31649239 -
Species: Human
Sample Types: Whole Cells
Applications: Western BlotA Stubb et al. (2019-10-18), Superresolution architecture of cornerstone focal adhesions in human pluripotent stem cells Nat Commun, 2019-110(1):4756.
PMID: 31628312 -
Species: Human
Sample Types: Whole Cells
Applications: ICCNM Peñaranda- et al. (2019-09-18), ER stress and UPR activation in glioblastoma: identification of a noncanonical PERK mechanism regulating GBM stem cells through SOX2 modulation Cell Death Dis, 2019-010(10):690.
PMID: 31534165 -
Species: Human
Sample Types: Whole Cells
Applications: ICCS Yang et al. (2019-07-09), An induced pluripotent stem cell line (TRNDi010-C) from a patient carrying a homozygous p.R401X mutation in the NGLY1 gene Stem Cell Res, 2019-039(0):101496.
PMID: 31326749 -
Species: Human,Mouse
Sample Types: Tissue Homogenates,Whole Cells
Applications: Western Blot,ICC,Flow Cytometry,ChIP-Seq,ChIPJ Yao et al. (2019-06-24), Elevated endothelial Sox2 causes lumen disruption and cerebral arteriovenous malformations J. Clin. Invest., 2019-0130(0).
PMID: 31232700 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCM Huang et al. (2019-06-13), Engineering Genetic Predisposition in Human Neuroepithelial Stem Cells Recapitulates Medulloblastoma Tumorigenesis Cell Stem Cell, 2019-00(0).
PMID: 31204176 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-PL Zurkirchen et al. (2019-05-16), Yin Yang 1 sustains biosynthetic demands during brain development in a stage-specific manner Nat Commun, 2019-010(1):2192.
PMID: 31097699 -
Species: Human
Sample Types: Whole Cells
Applications: ICCA Baskfield et al. (2019-05-15), An induced pluripotent stem cell line (TRNDi009-C) from a Niemann-Pick disease type A patient carrying a heterozygous p.L302P (c.905 T>C) mutation in the SMPD1 gene Stem Cell Res, 2019-038(0):101461.
PMID: 31132580 -
Species: Human
Sample Types: Whole Cells
S Howden et al. (2019-05-04), The use of simultaneous reprogramming and gene correction to generate an osteogenesis imperfecta patient COL1A1 c. 3936 G>T iPSC line and an isogenic control iPSC line Stem Cell Res, 2019-038(0):101453.
PMID: 31082677 -
Species: Human
Sample Types: Whole Cells
Applications: ICCC Calatayud et al. (2019-05-02), CRISPR/Cas9-mediated generation of a tyrosine hydroxylase reporter iPSC line for live imaging and isolation of dopaminergic neurons Sci Rep, 2019-09(1):6811.
PMID: 31048719 -
Species: Human
Sample Types: Whole Cells
Applications: ICCJ Hong et al. (2019-04-25), Generation of an induced pluripotent stem cell line (TRNDi008-A) from a Hunter syndrome patient carrying a hemizygous 208insC mutation in the IDS gene Stem Cell Res, 2019-037(0):101451.
PMID: 31071499 -
Species: Human
Sample Types: Whole Cells
Applications: ICCMC Regier et al. (2019-04-23), User-defined morphogen patterning for directing human cell fate stratification Sci Rep, 2019-09(1):6433.
PMID: 31015521 -
Species: Human
Sample Types: Whole Cells
Applications: ICCM Mura et al. (2019-04-13), Generation of the human induced pluripotent stem cell (hiPSC) line PSMi005-A from a patient carrying the KCNQ1-R190W mutation Stem Cell Res, 2019-037(0):101437.
PMID: 31009818 -
Species: Human
Sample Types: Whole Cells
Applications: ICCA Baskfield et al. (2019-04-12), Generation of an induced pluripotent stem cell line (TRNDi004-I) from a Niemann-Pick disease type B patient carrying a heterozygous mutation of p.L43_A44delLA in the SMPD1 gene Stem Cell Res, 2019-037(0):101436.
PMID: 31009819 -
Species: Human
Sample Types: Whole Cells
Applications: ICCYS Cheng et al. (2019-04-11), A human induced pluripotent stem cell line (TRNDi007-B) from an infantile onset Pompe patient carrying p.R854X mutation in the GAA gene Stem Cell Res, 2019-037(0):101435.
PMID: 31026687 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PSFB Fadhlullah et al. (2019-04-09), Pathogenic mutations in neurofibromin identifies a leucine-rich domain regulating glioma cell invasiveness Oncogene, 2019-038(27):5367-5380.
PMID: 30967630 -
Species: Human
Sample Types: Whole Cells
Applications: ICCM Mura et al. (2019-03-27), Generation of the human induced pluripotent stem cell (hiPSC) line PSMi004-A from a carrier of the KCNQ1-R594Q mutation Stem Cell Res, 2019-037(0):101431.
PMID: 30974404 -
Species: Human
Sample Types: Whole Cells
Applications: ICCW Huang et al. (2019-03-23), An induced pluripotent stem cell line (TRNDi006-A) from a MPS IIIB patient carrying homozygous mutation of p.Glu153Lys in the NAGLU gene Stem Cell Res, 2019-037(0):101427.
PMID: 30933722 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCM Sherman-Sa et al. (2019-03-21), SOX2 and SOX9 are markers of clinically aggressive disease in metastatic high-grade serous carcinoma Gynecol. Oncol., 2019-00(0).
PMID: 30904337 -
Species: Human
Sample Types: Whole Cells
Applications: Flow CytometryBW Stringer et al. (2019-03-20), A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma Sci Rep, 2019-09(1):4902.
PMID: 30894629 -
Species: Human
Sample Types: Whole Cells
Applications: ICCMA Ajmone-Cat et al. (2019-03-14), Increased FUS levels in astrocytes leads to astrocyte and microglia activation and neuronal death Sci Rep, 2019-09(1):4572.
PMID: 30872738 -
Species: Human
Sample Types: Whole Cells
Applications: ICCM Mura et al. (2019-03-06), Generation of the human induced pluripotent stem cell (hiPSC) line PSMi007-A from a Long QT Syndrome type 1 patient carrier of two common variants in the NOS1AP gene Stem Cell Res, 2019-036(0):101416.
PMID: 30878014 -
Species: Human
Sample Types: Whole Cells
Applications: ICCH Kim et al. (2019-02-21), Modeling G2019S-LRRK2 Sporadic Parkinson's Disease in 3D Midbrain Organoids Stem Cell Reports, 2019-00(0).
PMID: 30799274 -
Species: Human
Sample Types: Whole Cells
Applications: ICCR Li et al. (2019-02-15), Generation of an induced pluripotent stem cell line (TRNDi005-A) from a Mucopolysaccharidosis Type IVA (MPS IVA) patient carrying compound heterozygous p.R61W and p.WT405del mutations in the GALNS gene Stem Cell Res, 2019-036(0):101408.
PMID: 30797135 -
Species: Human
Sample Types: Whole Cells
Applications: ICC,Flow CytometryT Klein et al. (2019-02-02), Generation of two induced pluripotent stem cell lines from skin fibroblasts of sisters carrying a c.1094C>A variation in the SCN10A gene potentially associated with small fiber neuropathy Stem Cell Res, 2019-035(0):101396.
PMID: 30731422 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotS Melissarid et al. (2019-01-14), The effect of 2D and 3D cell cultures on treatment response, EMT profile and stem cell features in head and neck cancer Cancer Cell Int., 2019-019(0):16.
PMID: 30651721 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCL Loo et al. (2019-01-11), Single-cell transcriptomic analysis of mouse neocortical development Nat Commun, 2019-010(1):134.
PMID: 30635555 -
Species: Human
Sample Types: Whole Cells
Applications: ICCR Li et al. (2018-12-26), Generation of an induced pluripotent stem cell line (TRNDi003-A) from a Noonan syndrome with multiple lentigines (NSML) patient carrying a p.Q510P mutation in the PTPN11 gene Stem Cell Res, 2018-134(0):101374.
PMID: 30640061 -
Species: Human
Sample Types: Whole Cells
Applications: ICCR Li et al. (2018-12-05), Generation of an induced pluripotent stem cell line (TRNDi002-B) from a patient carrying compound heterozygous p.Q208X and p.G310G mutations in the NGLY1 gene Stem Cell Res, 2018-134(0):101362.
PMID: 30612078 -
Species: Human
Sample Types: Whole Cells
Applications: ICCCP Cui et al. (2018-11-07), Dynamic ubiquitylation of Sox2 regulates proteostasis and governs neural progenitor cell differentiation Nat Commun, 2018-19(1):4648.
PMID: 30405104 -
Species: Human
Sample Types: Whole Cells
Applications: ICCS Vallejo-Di et al. (2018-11-01), Generation of two induced pluripotent stem cells lines from a Mucopolysaccharydosis IIIB (MPSIIIB) patient Stem Cell Res, 2018-133(0):180-184.
PMID: 30408744 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCM Jeong et al. (2018-09-11), Generating inner ear organoids containing putative cochlear hair cells from human pluripotent stem cells Cell Death Dis, 2018-09(9):922.
PMID: 30206231 -
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: ICCR Nakai et al. (2018-08-15), Derivation of induced pluripotent stem cells in Japanese macaque (Macaca fuscata) Sci Rep, 2018-08(1):12187.
PMID: 30111816 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCSU Vay et al. (2018-08-13), The plasticity of primary microglia and their multifaceted effects on endogenous neural stem cells in vitro and in vivo J Neuroinflammation, 2018-015(1):226.
PMID: 30103769 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCT Klein et al. (2018-08-10), Generation of the human induced pluripotent stem cell line (UKWNLi001-A) from skin fibroblasts of a woman with Fabry disease carrying the X-chromosomal heterozygous c.708?G?>?C (W236C) missense mutation in exon 5 of the alpha-galactosidase-A gene Stem Cell Res, 2018-031(0):222-226.
PMID: 30130681 -
Species: Mouse
Sample Types: Cell Lysates
Applications: Western BlotS Kwak et al. (2018-07-27), Zinc finger proteins orchestrate active gene silencing during embryonic stem cell differentiation Nucleic Acids Res., 2018-00(0).
PMID: 29846698 -
Species: Human
Sample Types: Whole Cells
Applications: ICCX Gao et al. (2018-07-27), Generation of nine induced pluripotent stem cell lines as an ethnic diversity panel Stem Cell Res, 2018-031(0):193-196.
PMID: 30099336 -
Species: Rat
Sample Types: Whole Tissue
Applications: IHC-FrA Falnikar et al. (2018-06-07), Differential response in novel stem cell niches of the brain following cervical spinal cord injury and traumatic brain injury J. Neurotrauma, 2018-00(0).
PMID: 29471717 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCB López-Esco et al. (2018-05-08), The non-canonical Wnt-PCP pathway shapes the caudal neural plate Development, 2018-00(0).
PMID: 29636380 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCO Le et al. (2018-04-26), INK4a/ARF Expression Impairs Neurogenesis in the Brain of Irradiated Mice Stem Cell Reports, 2018-00(0).
PMID: 29706499 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotWA Pastor et al. (2018-04-25), TFAP2C regulates transcription in human naive pluripotency by opening enhancers Nat. Cell Biol., 2018-020(5):553-564.
PMID: 29695788 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCJY Lee et al. (2018-04-16), Neuronal SphK1 acetylates COX2 and contributes to pathogenesis in a model of Alzheimer's Disease Nat Commun, 2018-09(1):1479.
PMID: 29662056 -
Species: Human
Sample Types: Whole Cells
Applications: ICCM Mura et al. (2018-04-07), Generation of the human induced pluripotent stem cell (hiPSC) line PSMi002-A from a patient affected by the Jervell and Lange-Nielsen syndrome and carrier of two compound heterozygous mutations on the KCNQ1 gene Stem Cell Res, 2018-029(0):157-161.
PMID: 29677589 -
Species: Human
Sample Types: Whole Cells
Applications: ICCM Mura et al. (2018-04-06), Generation of the human induced pluripotent stem cell (hiPSC) line PSMi003-A from a patient affected by an autosomal recessive form of Long QT Syndrome type 1 Stem Cell Res, 2018-029(0):170-173.
PMID: 29684900 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCNS Corsini et al. (2018-04-05), Coordinated Control of mRNA and rRNA Processing Controls Embryonic Stem Cell Pluripotency and Differentiation Cell Stem Cell, 2018-022(4):543-558.e12.
PMID: 29625069 -
Species: Human
Sample Types: Whole Cells
Applications: ICCD Poppe et al. (2018-03-28), Genome Editing in Neuroepithelial Stem Cells to Generate Human Neurons with High Adenosine-Releasing Capacity Stem Cells Transl Med, 2018-00(0).
PMID: 29589874 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCC Aaberg-Jes et al. (2018-03-09), Co-expression of TIMP-1 and its cell surface binding partner CD63 in glioblastomas BMC Cancer, 2018-018(1):270.
PMID: 29523123 -
Species: Human
Sample Types: Whole Cells
Applications: ICCM Chen et al. (2018-02-06), Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs Front Cell Dev Biol, 2018-06(0):5.
PMID: 29468158 -
Species: Human
Sample Types: Whole Cells
Applications: ICCG V?fély et al. (2018-02-06), Characterization of calcium signals in human induced pluripotent stem cell-derived dentate gyrus neuronal progenitors and mature neurons, stably expressing an advanced calcium indicator protein Mol. Cell. Neurosci., 2018-00(0).
PMID: 29425968 -
Species: Mouse
Sample Types: Whole Tissue,Whole Cells
Applications: ICC,IHCA Yachie-Kin et al. (2018-01-29), Modeling signaling-dependent pluripotency with Boolean logic to predict cell fate transitions Mol. Syst. Biol., 2018-014(1):e7952.
PMID: 29378814 -
Species: Human
Sample Types: Whole Cells
Applications: ICCM Naumann et al. (2018-01-23), Impaired DNA damage response signaling by FUS-NLS mutations leads to neurodegeneration and FUS aggregate formation Nat Commun, 2018-09(1):335.
PMID: 29362359 -
Species: Rat
Sample Types: Cell Lysates
Applications: Western BlotA Alastrue-A et al. (2018-01-09), FM19G11 and Ependymal Progenitor/Stem Cell Combinatory Treatment Enhances Neuronal Preservation and Oligodendrogenesis after Severe Spinal Cord Injury Int J Mol Sci, 2018-019(1).
PMID: 29315225 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotM Okada et al. (2017-10-24), Repositioning CEP-1347, a chemical agent originally developed for the treatment of Parkinson's disease, as an anti-cancer stem cell drug Oncotarget, 2017-18(55):94872-94882.
PMID: 29212273 -
Species: Human
Sample Types: Whole Cells
Applications: ICCK Hirano et al. (2017-10-17), FAD influx enhances neuronal differentiation of human neural stem cells by facilitating nuclear localization of LSD1 FEBS Open Bio, 2017-17(12):1932-1942.
PMID: 29226080 -
Species: Human
Sample Types: Whole Cells
Applications: ICCA Hyysalo et al. (2017-09-12), Laminin ?5 substrates promote survival, network formation and functional development of human pluripotent stem cell-derived neurons in vitro Stem Cell Res, 2017-024(0):118-127.
PMID: 28926760 -
Species: Human
Sample Types: Whole Cells
Applications: ICCY Xu et al. (2017-05-19), Generation of an ASGR1 homozygous mutant human embryonic stem cell line WAe001-A-6 using CRISPR/Cas9 Stem Cell Res, 2017-022(0):29-32.
PMID: 28952928 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotJ Jung et al. (2017-05-18), Nicotinamide metabolism regulates glioblastoma stem cell maintenance JCI Insight, 2017-02(10).
PMID: 28515364 -
Species: Human
Sample Types: Whole Cells,Cell Lysates
Applications: ICC,Western BlotP Wang et al. (2017-04-25), HIF1? regulates single differentiated glioma cell dedifferentiation to stem-like cell phenotypes with high tumorigenic potential under hypoxia Oncotarget, 2017-08(17):28074-28092.
PMID: 28427209 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCG Kaufman et al. (2017-04-10), Spatial development of gingival fibroblasts and dental pulp cells: Effect of extracellular matrix Tissue Cell, 2017-00(0).
PMID: 28457531 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCX Wang et al. (2017-03-27), Purine synthesis promotes maintenance of brain tumor initiating cells in glioma Nat. Neurosci, 2017-00(0).
PMID: 28346452 -
Species: Human
Sample Types: Whole Cells
Applications: ICCTP Sharma et al. (2017-03-18), Patient-specific induced pluripotent stem cells to evaluate the pathophysiology of TRNT1-associated Retinitis pigmentosa Stem Cell Res, 2017-021(0):58-70.
PMID: 28390992 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PSS Jensen et al. (2017-03-07), Effects of the lysosomal destabilizing drug siramesine on glioblastoma in vitro and in vivo BMC Cancer, 2017-017(1):178.
PMID: 28270132 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotG Riddick et al. (2017-03-03), A Core Regulatory Circuit in Glioblastoma Stem Cells Links MAPK Activation to a Transcriptional Program of Neural Stem Cell Identity Sci Rep, 2017-07(0):43605.
PMID: 28256619 -
Species: Human
Sample Types: Whole Cells
Applications: ICCI Karakikes et al. (2017-02-28), A Comprehensive TALEN-Based Knockout Library for Generating Human Induced Pluripotent Stem Cell-Based Models for Cardiovascular Diseases Circ. Res, 2017-00(0).
PMID: 28246128 -
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry,ICCR Bayat Mokh et al. (2017-02-24), Acetazolamide potentiates the anti-tumor potential of HDACi, MS-275, in neuroblastoma BMC Cancer, 2017-017(1):156.
PMID: 28235409 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCS Falk et al. (2017-02-22), Time-Specific Effects of Spindle Positioning on Embryonic Progenitor Pool Composition and Adult Neural Stem Cell Seeding Neuron, 2017-093(4):777-791.e3.
PMID: 28231465 -
Species: Human
Sample Types: Whole Cells
Applications: ICCT Yamashita et al. (2017-02-13), Differentiation of oligodendrocyte progenitor cells from dissociated monolayer and feeder-free cultured pluripotent stem cells PLoS ONE, 2017-012(2):e0171947.
PMID: 28192470 -
Species: Mouse
Sample Types: Cell Lysates
Applications: Western BlotAG Alvarado et al. (2017-01-12), Glioblastoma Cancer Stem Cells Evade Innate Immune Suppression of Self-Renewal through Reduced TLR4 Expression Cell Stem Cell, 2017-020(4):450-461.e4.
PMID: 28089910 -
Species: Human
Sample Types: Whole Tissue,Whole Cells
Applications: IHC,ICCHO King et al. (2017-01-10), RAD51 Is a Selective DNA Repair Target to Radiosensitize Glioma Stem Cells Stem Cell Reports, 2017-08(1):125-139.
PMID: 28076755 -
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot(2016-11-23), SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis PLoS Biol., 2016-114(11):e1002581.
PMID: 27880766 -
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr(2016-09-19), ODZ1 allows glioblastoma to sustain invasiveness through a Myc-dependent transcriptional upregulation of RhoA Oncogene, 2016-00(0).
PMID: 27641332 -
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr(2016-09-16), Generation of a TLE1 homozygous knockout human embryonic stem cell line using CRISPR-Cas9 Stem Cell Res, 2016-017(2):430-432.
PMID: 27879218 -
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr(2016-09-15), Generation of a TLE3 heterozygous knockout human embryonic stem cell line using CRISPR-Cas9 Stem Cell Res, 2016-017(2):441-443.
PMID: 27879221 -
Species: Mouse
Sample Types: Whole Cells
Applications: IHC(2016-08-30), Enhancing the Three-Dimensional Structure of Adherent Gingival Fibroblasts and Spheroids via a Fibrous Protein-Based Hydrogel Cover Cells Tissues Organs (Print), 2016-00(0).
PMID: 27578009 -
Species: Human
Sample Types: Whole Cells
Applications: IHC-Fr(2016-08-02), Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A Stem Cells Transl Med, 2016-00(0).
PMID: 27484861 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr(2016-07-29), cGMP production of patient-specific iPSCs and photoreceptor precursor cells to treat retinal degenerative blindness Sci Rep, 2016-06(0):30742.
PMID: 27471043 -
Species: Porcine
Sample Types: Whole Cells
Applications: IHCAnnabelle Congras (2016-06-01), Non integrative strategy decreases chromosome instability and improves endogenous pluripotency genes reactivation in porcine induced pluripotent-like stem cells Sci Rep, 2016-06(0):27059.
PMID: 27245508 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC(2016-05-27), Cancer stem cell-secreted macrophage migration inhibitory factor stimulates myeloid derived suppressor cell function and facilitates glioblastoma immune evasion Stem Cells, 2016-00(0).
PMID: 27145382 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P(2016-05-12), Glioma Cells in the Tumor Periphery Have a Stem Cell Phenotype PLoS ONE, 2016-011(5):e0155106.
PMID: 27171431 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-FrGarriock R et al. (2015-05-01), Lineage tracing of neuromesodermal progenitors reveals novel Wnt-dependent roles in trunk progenitor cell maintenance and differentiation. Development, 2015-0142(9):1628-38.
PMID: 25922526 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotKim et al. (2015-04-08), SHMT2 drives glioma cell survival in ischaemia but imposes a dependence on glycine clearance. Nature, 2015-0520(7547):363-7.
PMID: 25855294 -
Species: Human
Sample Types: Whole Cells
Applications: ICCIacopino F et al. (2014-08-14), Isolation of cancer stem cells from three human glioblastoma cell lines: characterization of two selected clones. PLoS ONE, 2014-09(8):e105166.
PMID: 25121761 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCOnishi K et al. (2014-06-06), Local BMP-SMAD1 signaling increases LIF receptor-dependent STAT3 responsiveness and primed-to-naive mouse pluripotent stem cell conversion frequency. Stem Cell Reports, 2014-03(1):156-68.
PMID: 25068129 -
Species: Human
Sample Types: Whole Tissue
Applications: IHCYan K et al. (2014-05-01), Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy. Genes Dev, 2014-028(10):1085-100.
PMID: 24788093 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCSousa-Ferreira L et al. (2014-03-05), Fluoxetine induces proliferation and inhibits differentiation of hypothalamic neuroprogenitor cells in vitro. PLoS ONE, 2014-09(3):e88917.
PMID: 24598761 -
Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
Sample Types: Whole Cells
Applications: ICCOno T et al. (2014-02-05), A single-cell and feeder-free culture system for monkey embryonic stem cells. PLoS ONE, 2014-09(2):e88346.
PMID: 24505480 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotMiao et al. (2014-02-03), EphA2 promotes infiltrative invasion of glioma stem cells in vivo through cross-talk with Akt and regulates stem cell properties. Oncogene, 2014-034(5):558-67.
PMID: 24488013 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCSherwood et al. (2014-01-19), Discovery of directional and nondirectional pioneer transcription factors by modeling DNase profile magnitude and shape. Nat Biotechnol, 2014-032(2):171-8.
PMID: 24441470 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-FrAloia L et al. (2014-01-15), Zrf1 is required to establish and maintain neural progenitor identity. Genes Dev, 2014-028(2):182-97.
PMID: 24449271 -
Species: Mouse
Sample Types: Whole Cells
Applications: Western Blot,IHCIzumikawa et al. (2014-01-15), Chondroitin sulfate is indispensable for pluripotency and differentiation of mouse embryonic stem cells. Sci Rep, 2014-04(0):3701.
PMID: 24424429 -
Species: Mouse
Sample Types: Whole Tissue,Whole Cells,Tissue Homogenates
Applications: Western Blot,ICC,IHC-PMinamide et al. (2014-01-02), Antagonistic interplay between necdin and Bmi1 controls proliferation of neural precursor cells in the embryonic mouse neocortex. PLoS ONE, 2014-09(1):e84460.
PMID: 24392139 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCCapilla-Gonzalez V et al. (2014-01-01), The subventricular zone is able to respond to a demyelinating lesion after localized radiation. Stem Cells, 2014-032(1):59-69.
PMID: 24038623 -
Species: Human
Sample Types: Whole Cells
Applications: IHCVolonte A et al. (2013-11-25), Cancer-initiating cells from colorectal cancer patients escape from T cell-mediated immunosurveillance in vitro through membrane-bound IL-4. J Immunol, 2013-1192(1):523-32.
PMID: 24277698 -
Species: Mouse
Sample Types: Embryo
Applications: IHC-PDeVeale B et al. (2013-11-14), Oct4 is required ~E7.5 for proliferation in the primitive streak. PLoS Genet, 2013-19(11):e1003957.
PMID: 24244203 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCLi et al. (2013-04-22), Targeted deletion of the ERK5 MAP kinase impairs neuronal differentiation, migration, and survival during adult neurogenesis in the olfactory bulb. PLoS ONE, 2013-08(4):e61948.
PMID: 23630619 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCNajm et al. (2013-04-14), Transcription factor-mediated reprogramming of fibroblasts to expandable, myelinogenic oligodendrocyte progenitor cells. Nat Biotechnol, 2013-031(5):426-33.
PMID: 23584611 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCHaan et al. (2013-04-03), Fgf10-expressing tanycytes add new neurons to the appetite/energy-balance regulating centers of the postnatal and adult hypothalamus. J Neurosci, 2013-033(14):6170-80.
PMID: 23554498 -
Species: Human
Sample Types: Whole Cells
Applications: ICCMertens J et al. (2013-03-13), Embryonic stem cell-based modeling of tau pathology in human neurons. Am J Pathol, 2013-0182(5):1769-79.
PMID: 23499461 -
Species: Human
Sample Types: Whole Cells
Applications: ICCHayashi et al. (2012-09-24), Generation of corneal epithelial cells from induced pluripotent stem cells derived from human dermal fibroblast and corneal limbal epithelium. PLoS ONE, 2012-07(9):e45435.
PMID: 23029008 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotKamal MM et al. (2012-03-01), REST regulates oncogenic properties of glioblastoma stem cells. Stem Cells, 2012-030(3):405-14.
PMID: 22228704 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHCMahar I et al. (2011-10-19), Subchronic peripheral neuregulin-1 increases ventral hippocampal neurogenesis and induces antidepressant-like effects. PLoS ONE, 2011-16(10):e26610.
PMID: 22028923 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-FrLathia JD et al. (2011-09-22), Direct in vivo evidence for tumor propagation by glioblastoma cancer stem cells. PLoS ONE, 2011-06(9):e24807.
PMID: 21961046 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-PHibino N et al. (2011-05-12), Tissue-engineered vascular grafts form neovessels that arise from regeneration of the adjacent blood vessel. FASEB J., 2011-025(8):2731-9.
PMID: 21566209 -
Species: Human
Sample Types: Whole Cells
Applications: ICCWest FD et al. (2010-12-02), Human haploid cells differentiated from meiotic competent clonal germ cell lines that originated from embryonic stem cells. Stem Cells Dev., 2010-120(6):1079-88.
PMID: 20929355 -
Species: Human
Sample Types: Whole Cells
Applications: ICCKambal A et al. (2010-11-30), Generation of HIV-1 resistant and functional macrophages from hematopoietic stem cell-derived induced pluripotent stem cells. Mol. Ther., 2010-119(3):584-93.
PMID: 21119622 -
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-FrMak GK et al. (2010-05-09), Paternal recognition of adult offspring mediated by newly generated CNS neurons. Nat. Neurosci., 2010-013(6):753-8.
PMID: 20453850 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCRueger MA et al. (2010-05-05), Noninvasive imaging of endogenous neural stem cell mobilization in vivo using positron emission tomography. J. Neurosci., 2010-030(18):6454-60.
PMID: 20445071 -
Species: Human
Sample Types: Whole Tissue
Applications: IHC-PLiu A et al. (2010-05-01), Diagnostic utility of novel stem cell markers SALL4, OCT4, NANOG, SOX2, UTF1, and TCL1 in primary mediastinal germ cell tumors. Am. J. Surg. Pathol., 2010-034(5):697-706.
PMID: 20410807 -
Species: Human
Sample Types: Whole Cells
Applications: ICCWong CJ et al. (2010-01-22), Epigenetic changes to human umbilical cord blood cells cultured with three proteins indicate partial reprogramming to a pluripotent state. Exp. Cell Res., 2010-0316(6):927-39.
PMID: 20096686 -
Species: Human
Sample Types: Whole Cells
Applications: ICC(2009-04-01), The intracellular distribution of the ES cell totipotent markers OCT4 and Sox2 in adult stem cells differs dramatically according to commercial antibody used. J. Cell. Biochem., 2009-0106(5):867-77.
PMID: 19199344 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCRao RC et al. (2009-01-01), Efficient Serum-Free Derivation of Oligodendrocyte Precursors from Neural Stem Cell-Enriched Cultures. Stem Cells, 2009-00(0).
PMID: 18403757 -
Species: Mouse
Sample Types: Whole Cells
Applications: ICCLathia JD et al. (2008-12-17), Toll-like receptor 3 is a negative regulator of embryonic neural progenitor cell proliferation. J. Neurosci., 2008-128(51):13978-84.
PMID: 19091986 -
Species: Human
Sample Types: Cell Lysates
Applications: Western BlotNeganova I et al. (2008-09-22), Expression and functional analysis of G1 to S regulatory components reveals an important role for CDK2 in cell cycle regulation in human embryonic stem cells. Oncogene, 2008-028(1):20-30.
PMID: 18806832 -
Species: Human
Sample Types: Whole Cells
Applications: ICCVarelas X et al. (2008-06-22), TAZ controls Smad nucleocytoplasmic shuttling and regulates human embryonic stem-cell self-renewal. Nat. Cell Biol., 2008-010(7):837-48.
PMID: 18568018 -
Species: Human
Sample Types: Whole Cells
Applications: ICC,Flow CytometryGunther HS et al. (2007-11-26), Glioblastoma-derived stem cell-enriched cultures form distinct subgroups according to molecular and phenotypic criteria. Oncogene, 2007-127(20):2897-909.
PMID: 18037961 -
Species: Human
Sample Types: Whole Cells
Applications: ICCHattori Y et al. (2007-10-15), Identification of a neuron-specific human gene, KIAA1110, that is a guanine nucleotide exchange factor for ARF1. Biochem. Biophys. Res. Commun., 2007-1364(4):737-42.
PMID: 17981261 -
Species: Human
Sample Types: Cell Lysates,Whole Cells,Whole Tissue
Applications: IHC-P,Western Blot,ICCSchmitz M et al. (2007-03-20), Identification of SOX2 as a novel glioma-associated antigen and potential target for T cell-based immunotherapy. Br. J. Cancer, 2007-096(8):1293-301.
PMID: 17375044 -
Species: Human
Sample Types: Whole Cells
Applications: ICCPankratz MT et al. (2007-03-01), Directed neural differentiation of human embryonic stem cells via an obligated primitive anterior stage. Stem Cells, 2007-025(6):1511-20.
PMID: 17332508 -
Species: Human
Sample Types: Whole Cells
Applications: ICCShin S et al. (2007-02-01), Whole genome analysis of human neural stem cells derived from embryonic stem cells and stem and progenitor cells isolated from fetal tissue. Stem Cells, 2007-025(5):1298-306.
PMID: 17272497 -
Species: Rat
Sample Types: Whole Cells
Applications: ICCKobayashi T et al. (2006-07-27), Intracerebral infusion of glial cell line-derived neurotrophic factor promotes striatal neurogenesis after stroke in adult rats. Stroke, 2006-037(9):2361-7.
PMID: 16873711
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Customer Reviews for Human/Mouse/Rat SOX2 Antibody (13)
Customer Images
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Application: Immunocytochemistry/ImmunofluorescenceSample Tested: glioblastoma cellsSpecies: HumanVerified Customer | Posted 08/06/2021On the photo SOX2 is red, nuclear DAPI is blue.
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Application: Immunocytochemistry/ImmunofluorescenceSample Tested: iPS2 human induced pluripotent stem cellsSpecies: HumanVerified Customer | Posted 10/18/2018Cells: human induced pluripotent stem cells Primary antibody: anti-human SOX2 (1:200), O/N incubation at 4 degrees Secondary antibody: anti-mouse AF488
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Application: ImmunohistochemistrySample Tested: Brain (forebrain)Species: MouseVerified Customer | Posted 02/16/2017Red: sox2. Green: ki67. Blue: DAPI. Postnatal day 7 sub-ventricular zone. 2% PFA fixed. Heat-mediated antigen retrieval. Blocked with 10% donkey serum, 0.5% Triton in PBS for 1h. Dilution 1:100.
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Application: Immunocytochemistry/ImmunofluorescenceSample Tested: Neural progenitor cellsSpecies: HumanVerified Customer | Posted 02/03/2017
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Application: Immunocytochemistry/ImmunofluorescenceSample Tested: Induced pluripotent stem cellsSpecies: HumanVerified Customer | Posted 12/15/2016I used this antibody to test Sox2 expression in iPS cells derived from fibroblasts of Sanfilippo syndrome C patients.
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Application: Immunocytochemistry/ImmunofluorescenceSample Tested: human NSCSpecies: HumanVerified Customer | Posted 10/26/2015Specificity: Specific
Sensitivity: Reasonably sensitive
Buffer: 1% BSA + 0.3% Triton X-100 in PBS
Dilution: 1/100 -
Application: Immunocytochemistry/ImmunofluorescenceSample Tested: human fibroblast and neural stem cellsSpecies: HumanVerified Customer | Posted 10/26/2015Specificity: Specific
Sensitivity: Reasonably sensitive
Buffer: 1% BSA + 0.3% Triton X-100 in PBS
Dilution: 1/100 -
Application: Western BlotSample Tested: Human cellsSpecies: HumanVerified Customer | Posted 10/26/2015Specificity: Specific
Sensitivity: Sensitive
Buffer: 5% BSA in TBST
Dilution: 1/1000 -
Application: ImmunofluorescenceSample Tested: See PMID 22791629Species: RatVerified Customer | Posted 02/16/2015
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Application: ImmunofluorescenceSample Tested: See PMID 19824823Species: HumanVerified Customer | Posted 02/16/2015
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Application: ImmunofluorescenceSample Tested: See PMID 19825428Species: MouseVerified Customer | Posted 02/16/2015
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Application: ImmunofluorescenceSample Tested: See PMID 23658023Species: HumanVerified Customer | Posted 02/16/2015
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Application: ImmunofluorescenceSample Tested: See PMID 22573702Species: OtherVerified Customer | Posted 02/16/2015
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Reconstitution Calculator
The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.