Recombinant Human IL-1 alpha/IL-1F1 Protein Best Seller

Name: Recombinant Human IL-1 alpha/IL-1F1 Protein
Brand: R&D Systems
SKU: 200-LA
Rating: 5 (8 reviews)

Catalog # 200-LA | R&D Systems, Inc. a Bio-Techne Brand

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Citations (59)

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Setting the standard in quality research reagents

Key Product Details

Source:	E. coli
Accession #:	Q53QF9
Applications:	Bioactivity

View Full Technical Details for Recombinant Human IL-1 alpha/IL-1F1 Protein

Technical Data
Citations (59) / Reviews (8)

Product Specifications for Recombinant Human IL-1 alpha/IL-1F1 Protein

Source	E. coli-derived human IL-1 alpha/IL-1F1 protein Ser113-Ala271
Purity	>97%, by SDS-PAGE under reducing conditions and visualized by silver stain
Endotoxin level	<0.10 EU per 1 μg of the protein by the LAL method.
N-terminal sequence Analysis	Ser113
Predicted Molecular Mass	18 kDa
SDS-PAGE	18 kDa
Activity	Measured in a cell proliferation assay using D10.G4.1 mouse helper T cells. Symons, J.A. et al. (1987) in Lymphokines and Interferons, a Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 272. The ED₅₀ for this effect is 1‑6 pg/mL.

Scientific Data Examples for Recombinant Human IL-1 alpha/IL-1F1 Protein

	Recombinant Human IL-1 alpha/IL-1F1 Protein Bioactivity Recombinant Human IL-1 alpha /IL-1F1 (Catalog # 200-LA) stimulates cell proliferation of the D10.G4.1 mouse helper T cell line. The ED₅₀ for this effect is 1-6 pg/mL.
	Recombinant Human IL-1 alpha/IL-1F1 Protein SDS-PAGE 1 μg/lane of Recombinant Human IL-1 alpha /IL-1F1 was resolved with SDS-PAGE under reducing (R) conditions and visualized by silver staining, showing a single band at 18 kDa.

Formulation, Preparation and Storage

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

200-LA

Carrier

Formulation	Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution	Reconstitute at 10 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping	The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after reconstitution. 3 months, -20 to -70 °C under sterile conditions after reconstitution.

200-LA/CF

Carrier Free

Formulation	Supplied as a 0.2 μm filtered solution in PBS.
Shipping	The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage:	Use a manual defrost freezer and avoid repeated freeze-thaw cycles. 12 months from date of receipt, -20 to -70 °C as supplied. 1 month, 2 to 8 °C under sterile conditions after opening.

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IL-1 alpha/IL-1F1

Interleukin 1 (IL-1) is a name that designates two proteins, IL-1 alpha and IL-1 beta, which are the products of distinct genes, but which show approximately 25% amino acid sequence identity and which recognize the same cell surface receptors. Although IL-1 production is generally considered to be a consequence of inflammation, recent evidence suggests that IL-1 is also temporarily upregulated during bone formation and the menstrual cycle and can be induced in response to nervous system stimulation. In response to classic stimuli produced by inflammatory agents, infections or microbial endotoxins, a dramatic increase in the production of IL-1 by macrophages and various other cells is seen. Cells in particular known to produce IL-1 include osteoblasts, monocytes, macrophages, keratinocytes, Kupffer cells, hepatocytes, thymic and salivary gland epithelium, Schwann cells, fibroblasts and glia (oligodendroglia, astrocytes and microglia).

IL-1 alpha and IL-1 beta are both synthesized as 31 kDa precursors that are subsequently cleaved into proteins with molecular weights of approximately 17,000 Da. Neither precursor contains a typical hydrophobic signal peptide sequence and most of the precursor form of IL-1 alpha remains in the cytosol of cells, although there is evidence for a membrane-bound form of the precursor form of IL-1 alpha. The IL-1 alpha precursor reportedly shows full biological activity in the EL-4 assay. Among various species, the amino acid sequence of mature IL-1 alpha is conserved 60% to 70% and human IL-1 has been found to be biologically active on murine cell lines. Both forms of IL-1 bind to the same receptors, designated type I and type II. Evidence suggests that only the type I receptor is capable of signal transduction and that the type II receptor may function as a decoy, binding IL-1 and thus preventing binding of IL-1 to the type I receptor.

Item	Value
Long Name	Interleukin 1 alpha
Entrez Gene IDs	3552 (Human); 16175 (Mouse); 24493 (Rat); 397094 (Porcine); 101926546 (Cynomolgus Monkey)
Alternate Names	BAF, Hematopoietin-1, IL-1 alpha, IL-1A, IL-1F1, IL1, IL1 alpha, IL1-ALPHA, IL1A, IL1F1, IL1F1hematopoietin-1, LAF, LEM, interleukin 1, alpha, interleukin-1 alpha, preinterleukin 1 alpha, pro-interleukin-1-alpha

Citations for Recombinant Human IL-1 alpha/IL-1F1 Protein (59)

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Citations are publications that use Bio-Techne products. Selected citations for Recombinant Human IL-1 alpha/IL-1F1 Protein include:

Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Karema-Jokinen et al. (2023-05-01), Crosstalk of protein clearance, inflammasome, and Ca2+ channels in retinal pigment epithelium derived from age-related macular degeneration patients The Journal of biological chemistry
PMID: 37137441
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

P Szpakowski et al. (2022-07-22), Human Primary Astrocytes Differently Respond to Pro- and Anti-Inflammatory Stimuli Biomedicines, 2022-010(8).
PMID: 35892669
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MC Ebeling et al. (2022-06-30), Inflammasome Activation in Retinal Pigment Epithelium from Human Donors with Age-Related Macular Degeneration Cells, 2022-011(13).
PMID: 35805159
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Filidou et al. (2022-04-20), Anti-Inflammatory and Anti-Fibrotic Effect of Immortalized Mesenchymal-Stem-Cell-Derived Conditioned Medium on Human Lung Myofibroblasts and Epithelial Cells International Journal of Molecular Sciences, 2022-023(9).
PMID: 35562961
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Y Zhu et al. (2022-03-13), Orally-active, clinically-translatable senolytics restore alpha-Klotho in mice and humans EBioMedicine, 2022-00(0):103912.
PMID: 35292270
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M McAleavy et al. (2021-11-01), The Activin/FLRG pathway associates with poor COVID-19 outcomes in hospitalized patients Molecular and Cellular Biology, 2021-10(0):MCB0046721.
PMID: 34723652
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

H Sheldon et al. (2021-10-19), ELTD1 Activation Induces an Endothelial-EMT Transition to a Myofibroblast Phenotype International Journal of Molecular Sciences, 2021-122(20).
PMID: 34681953
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

R Biavasco et al. (2021-07-27), Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis Nature Communications, 2021-012(1):4559.
PMID: 34315896
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

N Bhattarai et al. (2021-06-06), Hydroquinone Induces NLRP3-Independent IL-18 Release from ARPE-19 Cells Cells, 2021-010(6).
PMID: 34204067
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Ranta-Aho et al. (2021-05-05), TAS-116, a Well-Tolerated Hsp90 Inhibitor, Prevents the Activation of the NLRP3 Inflammasome in Human Retinal Pigment Epithelial Cells International Journal of Molecular Sciences, 2021-022(9).
PMID: 34062977
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M Hayn et al. (2021-04-27), Systematic functional analysis of SARS-CoV-2 proteins uncovers viral innate immune antagonists and remaining vulnerabilities Cell Reports, 2021-035(7):109126.
PMID: 33974846
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

K Bernau et al. (2021-03-02), Interleukin-1&alpha Is a Critical Mediator of the Response of Human Bronchial Fibroblasts to Eosinophilic Inflammation Cells, 2021-010(3).
PMID: 33801398
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

X Li et al. (2020-11-13), 18F-FHBG PET-CT Reporter Gene Imaging of Adoptive CIK Cell Transfer Immunotherapy for Breast Cancer in a Mouse Model Onco Targets Ther, 2020-113(0):11659-11668.
PMID: 33223839
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

D Liu et al. (2020-10-22), Soluble Compounds Released by Hypoxic Stroma Confer Invasive Properties to Pancreatic Ductal Adenocarcinoma Biomedicines, 2020-18(11).
PMID: 33105540
Species: Mouse
Sample Types: Reference Standard

J Sun et al. (2020-09-23), The Pseudomonas aeruginosa protease LasB directly activates IL-1&beta EBioMedicine, 2020-060(0):102984.
PMID: 32979835
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CJ Cunningham et al. (2020-01-21), Systemic conditioned medium treatment from interleukin-1 primed mesenchymal stem cells promotes recovery after stroke Stem Cell Res Ther, 2020-011(1):32.
PMID: 31964413
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

NE Powers et al. (2019-12-09), PASylation of IL-1 Receptor antagonist (IL-1Ra) retains IL-1 blockade and extends its duration in mouse urate crystal-induced peritonitis J. Biol. Chem., 2019-10(0).
PMID: 31819009
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

N Piippo et al. (2018-08-23), Oxidative Stress is the Principal Contributor to Inflammasome Activation in Retinal Pigment Epithelium Cells with Defunct Proteasomes and Autophagy Cell. Physiol. Biochem., 2018-049(1):359-367.
PMID: 30138927
Species: Bovine
Sample Types: Whole Tissue
Applications: Bioassay

KC Ravindra et al. (2018-05-23), Chemoproteomics of matrix metalloproteases in a model of cartilage degeneration suggests functional biomarkers associated with posttraumatic osteoarthritis J. Biol. Chem., 2018-00(0).
PMID: 29794029
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Couderc et al. (2017-07-14), Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis PLoS ONE, 2017-012(7):e0181486.
PMID: 28708859
Species: Human
Sample Types: Plasma
Applications: Control

JH von Steman et al. (2017-06-30), Prevalence and correlation of cytokine-specific autoantibodies with epidemiological factors and C-reactive protein in 8,972 healthy individuals: Results from the Danish Blood Donor Study PLoS ONE, 2017-012(6):e0179981.
PMID: 28665954
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

B Tian et al. (2017-05-24), Atorvastatin Promotes Phagocytosis and Attenuates Pro-Inflammatory Response in Human Retinal Pigment Epithelial Cells Sci Rep, 2017-07(1):2329.
PMID: 28539592
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

E Redondo-Ca et al. (2017-04-17), Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro Stem Cell Res Ther, 2017-08(1):79.
PMID: 28412968
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

KM Perrott et al. (2017-04-04), Apigenin suppresses the senescence-associated secretory phenotype and paracrine effects on breast cancer cells Geroscience, 2017-039(2):161-173.
PMID: 28378188
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sojoong Choi (2016-12-28), Inflammatory hypoxia induces syndecan-2 expression through IL-1?-mediated FOXO3a activation in colonic epithelia FASEB J, 2016-10(0).
PMID: 28031321
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2016-09-20), Inflammatory Adipokines Decrease Expression of Two High Molecular Weight Isoforms of Tropomyosin Similar to the Change in Type 2 Diabetic Patients PLoS ONE, 2016-011(9):e0162908.
PMID: 27649540
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MD Ballantyne et al. (2016-04-06), Smooth Muscle Enriched Long Non-Coding RNA (SMILR) Regulates Cell Proliferation Circulation, 2016-00(0).
PMID: 27052414
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

S Robert et al. (2016-04-05), Characterization of the MMP/TIMP Imbalance and Collagen Production Induced by IL-1? or TNF-? Release from Human Hepatic Stellate Cells PLoS ONE, 2016-011(4):e0153118.
PMID: 27046197
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dankbar B et al. (2015-08-03), Myostatin is a direct regulator of osteoclast differentiation and its inhibition reduces inflammatory joint destruction in mice. Nat Med, 2015-021(9):1085-90.
PMID: 26236992
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Laberge R et al. (2015-07-06), MTOR regulates the pro-tumorigenic senescence-associated secretory phenotype by promoting IL1A translation. Nat Cell Biol, 2015-017(8):1049-61.
PMID: 26147250
Species: Rat
Sample Types: In Vivo
Applications: In Vivo

Fernandez-Bustamante A et al. (2015-07-06), Brief Glutamine Pretreatment Increases Alveolar Macrophage CD163/Heme Oxygenase-1/p38-MAPK Dephosphorylation Pathway and Decreases Capillary Damage but Not Neutrophil Recruitment in IL-1/LPS-Insufflated Rats. PLoS ONE, 2015-010(7):e0130764.
PMID: 26147379
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Rabeony H et al. (2014-07-10), Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1alpha, TNFalpha and oncostatin M. PLoS ONE, 2014-09(7):e101937.
PMID: 25010647
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gschwandtner M et al. (2014-04-02), Fetal human keratinocytes produce large amounts of antimicrobial peptides: involvement of histone-methylation processes. J Invest Dermatol, 2014-0134(8):2192-201.
PMID: 24694903
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gieseke F et al. (2013-07-23), Proinflammatory stimuli induce galectin-9 in human mesenchymal stromal cells to suppress T-cell proliferation. Eur J Immunol, 2013-043(10):2741-9.
PMID: 23817958
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Wilson TR et al. (2012-07-26), Widespread potential for growth-factor-driven resistance to anticancer kinase inhibitors. Nature, 2012-0487(7408):505-9.
PMID: 22763448
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

(2012-07-16), Interleukin-1alpha controls allergic sensitization to inhaled house dust mite via the epithelial release of GM-CSF and IL-33. J. Exp. Med., 2012-0209(8):1505-17.
PMID: 22802353
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Jung DW et al. (2010-07-15), Tumor-stromal crosstalk in invasion of oral squamous cell carcinoma: a pivotal role of CCL7. Int. J. Cancer, 2010-0127(2):332-44.
PMID: 19937793
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gudjonsson JE et al. (2010-04-08), Evidence for altered Wnt signaling in psoriatic skin. J. Invest. Dermatol., 2010-0130(7):1849-59.
PMID: 20376066
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Guilloteau K et al. (2010-03-24), Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis. J. Immunol., 2010-0184(0):5263-70.
PMID: 20335534
Sample Types: N/A
Applications: ELISA (Standard)

Gonzalez RM et al. (2008-04-19), Development and validation of sandwich ELISA microarrays with minimal assay interference. J. Proteome Res., 2008-07(6):2406-14.
PMID: 18422355
Sample Types: N/A
Applications: ELISA (Standard)

Biancotto A et al. (2008-03-01), Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo. AIDS Res. Hum. Retroviruses, 2008-024(3):453-62.
PMID: 18327985
Sample Types: N/A
Applications: ELISA (Standard)

Pfleger C et al. (2007-10-22), Effect of serum content and diluent selection on assay sensitivity and signal intensity in multiplex bead-based immunoassays. J. Immunol. Methods, 2007-1329(1):214-8.
PMID: 17964594
Sample Types: N/A
Applications: ELISA (Standard)

Todd J et al. (2007-09-21), Ultrasensitive flow-based immunoassays using single-molecule counting. Clin. Chem., 2007-053(11):1990-5.
PMID: 17890441
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kelley MJ et al. (2007-06-01), Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork. Invest. Ophthalmol. Vis. Sci., 2007-048(6):2634-43.
PMID: 17525194
Sample Types: N/A
Applications: Western Blot

Wilson HL et al. (2007-03-12), P2X receptor characterization and IL-1/IL-1Ra release from human endothelial cells. Br. J. Pharmacol., 2007-0151(1):115-27.
PMID: 17351655
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Brechter AB et al. (2007-03-01), Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression. Arthritis Rheum., 2007-056(3):910-23.
PMID: 17328065
Sample Types: N/A
Applications: ELISA (Standard)

Biancotto A et al. (2007-02-08), Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1. Blood, 2007-0109(10):4272-9.
PMID: 17289812
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Gleissner CA et al. (2007-01-01), IL-10 inhibits endothelium-dependent T cell costimulation by up-regulation of ILT3/4 in human vascular endothelial cells. Eur. J. Immunol., 2007-037(1):177-92.
PMID: 17163451
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Johnson LA et al. (2006-11-20), An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium. J. Exp. Med., 2006-1203(12):2763-77.
PMID: 17116732
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Abe Y et al. (2006-10-04), L5, the most electronegative subfraction of plasma LDL, induces endothelial vascular cell adhesion molecule 1 and CXC chemokines, which mediate mononuclear leukocyte adhesion. Atherosclerosis, 2006-1192(1):56-66.
PMID: 17022986
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Li Y et al. (2006-05-11), Transforming growth factor-alpha: a major human serum factor that promotes human keratinocyte migration. J. Invest. Dermatol., 2006-0126(9):2096-105.
PMID: 16691197
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Palmer G et al. (2005-07-21), Pre-interleukin-1alpha expression reduces cell growth and increases interleukin-6 production in SaOS-2 osteosarcoma cells: Differential inhibitory effect of interleukin-1 receptor antagonist (icIL-1Ra1). Cytokine, 2005-031(2):153-60.
PMID: 15923123
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dulos J et al. (2005-03-01), CYP7B expression and activity in fibroblast-like synoviocytes from patients with rheumatoid arthritis: regulation by proinflammatory cytokines. Arthritis Rheum., 2005-052(3):770-8.
PMID: 15751070
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kao CY et al. (2004-09-01), IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways. J. Immunol., 2004-0173(5):3482-91.
PMID: 15322213
Species: Bovine
Sample Types: Whole Cells
Applications: Bioassay

Morita K et al. (2004-08-04), Interleukin-1 inhibits voltage-dependent P/Q-type Ca2+ channel associated with the inhibition of the rise of intracellular free Ca2+ concentration and catecholamine release in adrenal chromaffin cells. Biochim. Biophys. Acta, 2004-01673(3):160-9.
PMID: 15279887
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kawano Y et al. (2004-08-01), The effect of inflammatory cytokines on secretion of macrophage colony-stimulating factor and monocyte chemoattractant protein-1 in human granulosa cells. Am. J. Reprod. Immunol., 2004-052(2):124-8.
PMID: 15274652
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Smith DE et al. (2003-01-01), The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action. Immunity, 2003-018(1):87-96.
PMID: 12530978
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Szabowski A et al. (2000-11-22), c-Jun and JunB antagonistically control cytokine-regulated mesenchymal-epidermal interaction in skin. Cell, 2000-1103(5):745-55.
PMID: 11114331
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Lerner UH et al. (1998-06-01), Gingival crevicular fluid from patients with periodontitis contains bone resorbing activity. Eur. J. Oral Sci., 1998-0106(3):778-87.
PMID: 9672100

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Customer Reviews for Recombinant Human IL-1 alpha/IL-1F1 Protein (8)

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Recombinant Human IL-1 alpha/IL-1F1 Protein

Name: Anonymous

Application: In vitro bioactivity in cell culture

Verified Customer | Posted 09/16/2021
Recombinant Human IL-1 alpha/IL-1F1 Protein

Name: Anonymous

Application: In vitro bioactivity in cell culture

Verified Customer | Posted 04/13/2021
Recombinant Human IL-1 alpha/IL-1F1 Protein

Name: Anonymous

Application: In vitro bioactivity in cell culture

Verified Customer | Posted 12/22/2020
Name: Anonymous

Application: Cell migration/motility

Verified Customer | Posted 06/04/2019
Recombinant Human IL-1 alpha/IL-1F1 Protein

Name: Joseph Moore

Application: In vitro bioactivity in cell culture

Reason for Rating: We used this in chondral explants as a positive control for osteoarthritis. It increases activity of comp, MMP13, and many other marks for OA. This is our labs staple IL and it works prefect every time.

Verified Customer | Posted 05/14/2019
Name: Anonymous

Application: Cell migration/motility

Verified Customer | Posted 01/30/2019
Name: Anonymous

Application: Cell migration/motility

Verified Customer | Posted 11/01/2018
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Application: In vitro bioactivity in cell culture

Verified Customer | Posted 03/30/2018

Recombinant Human IL-1 alpha/IL-1F1 Protein Best Seller

Catalog # 200-LA | R&D Systems, Inc. a Bio-Techne Brand

Key Product Details

Product Specifications for Recombinant Human IL-1 alpha/IL-1F1 Protein

Scientific Data Examples for Recombinant Human IL-1 alpha/IL-1F1 Protein

Formulation, Preparation and Storage

Carrier Free

200-LA

Carrier

200-LA/CF

Carrier Free

Reconstitution Calculator

Background: IL-1 alpha/IL-1F1

Citations for Recombinant Human IL-1 alpha/IL-1F1 Protein (59)

Customer Reviews for Recombinant Human IL-1 alpha/IL-1F1 Protein (8)

Customer Images

Recombinant Human IL-1 alpha/IL-1F1 Protein

Recombinant Human IL-1 alpha/IL-1F1 Protein

Recombinant Human IL-1 alpha/IL-1F1 Protein

Recombinant Human IL-1 alpha/IL-1F1 Protein

Product Documents for Recombinant Human IL-1 alpha/IL-1F1 Protein

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