48 results for "reprogramming" in Products

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48 results for "reprogramming" in Products

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Y-27632 dihydrochloride

Catalog #: 1254
(12)
Citations (251)

Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component

Alternate Names : y27632, Y-27632 2HCl, ROCK inhibitor, ROCK1 inhibitor
Chemical Name : trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity : ≥98% (HPLC)
ROCK inhibition by Y-27632 and immunostaining of skeletal myogenic differentiation of MESP1+ mesoderm,
(2)

SB 431542

Catalog #: 1614
(7)
Citations (262)

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name : 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity : ≥99% (HPLC)
dopaminergic neurons derived from hiPSCs using SB 431542
(2)

CHIR 99021

Catalog #: 4423
(16)
Citations (409)

Highly selective GSK-3 inhibitor; acts as Wnt activator

Alternate Names : CHIR99021, CT99021
Chemical Name : 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity : ≥98% (HPLC)
Cardiomyocyte derived from human induced pluripotent stem cells (hiPSCs) using CHIR 99021.
(2)

3-Deazaneplanocin A hydrochloride

Catalog #: 4703
Citations (4)

EZH2 histone methyltransferase inhibitor

Alternate Names : DZNep, NSC 617989
Chemical Name : (1S,2R,5R)-5-(4-Amino-1H-imidazo[4,5-c]pyridin-1-yl)-3-(hydroxymethyl)-3-cyclopentene-1,2-diol hydrochloride
Purity : ≥98% (HPLC)
EZH2 histone methyltransferase inhibitor

L-Ascorbic acid

Catalog #: 4055
(2)
Citations (16)

Enhances the generation of iPSCs; increases reprogramming efficiency

Alternate Names : L-Ascorbate, Vitamin C
Chemical Name : 3-Oxo-L-gulofuranolactone
Purity : ≥99% (HPLC)
Enhances the generation of iPSCs; increases reprogramming efficiency

IWP 2

Catalog #: 3533
(2)
Citations (102)

PORCN inhibitor; inhibits Wnt processing and secretion

Chemical Name : N-(6-Methyl-2-benzothiazolyl)-2-[(3,4,6,7-tetrahydro-4-oxo-3-phenylthieno[3,2-d]pyrimidin-2-yl)thio]-acetamide
Purity : ≥98% (HPLC)
PORCN inhibitor; inhibits Wnt processing and secretion

Thiazovivin

Catalog #: 3845
Citations (16)

ROCK inhibitor ; improves the efficiency of fibroblast reprogramming and induction of iPSCs

Chemical Name : N-Benzyl-[2-(pyrimidin-4-yl)amino]thiazole-4-carboxamide
Purity : ≥98% (HPLC)
ROCK inhibitor ; improves the efficiency of fibroblast reprogramming and induction of iPSCs

Tocriscreen Stem Cell Library

Catalog #: 7340
Citations (3)

A library of 120 stem cell compounds (100 μL 10 mM DMSO solutions) to explore stem cell reprogramming, differentiation, proliferation and signaling

Tocriscreen stem cell compound library logo

Chroman 1

Catalog #: 7163

Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogenesis

Chemical Name : (3S)-N-[2-[2-(Dimethylamino)ethoxy]-4-(1H-pyrazol-4-yl)phenyl]-3,4-dihydro-6-methoxy-2H-1-benzopyran-3-carboxamide dihydrochloride
Purity : ≥98% (HPLC)
Highly potent and selective ROCK 2 inhibitor; improves cell survival after cryogenesis

Valproic acid, sodium salt

Catalog #: 2815
(2)
Citations (4)

Histone deacetylase inhibitor

Alternate Names : VPA, Sodium Valproate
Chemical Name : Sodium 2-propylpentanoate
Histone deacetylase inhibitor
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