576 results for "kinase inhibitors" in Products
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576 results for "kinase inhibitors" in Products
A bioactive compound library of 210 kinase inhibitors (100 μL 10 mM DMSO solutions) for high-throughput screening, high-content screening and chemical biology applications
Selective inhibitor of myosin light chain kinase
Alternate Names : | Myosin Light Chain Kinase Inhibitor Peptide 18 |
Purity : | ≥95% (HPLC) |
Potent protein kinase A inhibitor
Alternate Names : | Protein kinase inhibitor-(6-22)-amide, PKI-(6-22)-amide |
Purity : | ≥95% (HPLC) |
Promotes Akt hyperphosphorylation; decreases phosphorylation of Akt substrates
Chemical Name : | 6-(2-Benzothiazolyl)-1-ethyl-2-[(1E)-2-(methylphenylamino)ethenyl]-3-phenyl-1H-benzimidazolium iodide |
Purity : | ≥98% (HPLC) |
Selective FAK inhibitor
Alternate Names : | Y15, NSC 677249 |
Chemical Name : | 1,2,4,5-Benzenetetramine tetrahydrochloride |
Potent RIPK2 inhibitor
Chemical Name : | 3-(Benzoylamino)-4-methyl-N-[3-(1-methyl-1H-imidazol-2-yl)phenyl]benzamide |
Purity : | ≥98% (HPLC) |
IRAK4 and IRAK1 inhibitor
Chemical Name : | N-[1-[2-(4-Morpholinyl)ethyl]-1H-benzimidazol-2-yl]-3-nitrobenzamide |
Purity : | ≥98% (HPLC) |
Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component
Alternate Names : | y27632, Y-27632 2HCl, ROCK inhibitor, ROCK1 inhibitor |
Chemical Name : | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
Purity : | ≥98% (HPLC) |
Y-27632 synthesized to cGMP guidelines
Chemical Name : | trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride |
Purity : | ≥99% |
Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7
Chemical Name : | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
Purity : | ≥99% (HPLC) |
SB 431542 synthesized to cGMP guidelines
Chemical Name : | 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide |
Purity : | ≥99% |
Highly selective GSK-3 inhibitor; acts as Wnt activator
Alternate Names : | CHIR99021, CT99021 |
Chemical Name : | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
Purity : | ≥98% (HPLC) |
CHIR 99021 synthesized to cGMP guidelines
Chemical Name : | 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile |
Purity : | ≥99% |
Selective inhibitor of TGF-βRI, ALK4 and ALK7
Chemical Name : | 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide |
Purity : | ≥98% (HPLC) |
Non-selective protein kinase inhibitor
Alternate Names : | AM-2282 |
Chemical Name : | [9S-(9α,10β,11β,13α)]-2,3,10,11,12,13-Hexahydro-10-methoxy-9-methyl-11-(methylamino)-9,13-epoxy-1H,9H-diindolo[1,2,3-gh:3',2',1'-lm]pyrrolo[3,4-j][1,7]benzodiazonin-1-one |
Purity : | ≥98% (HPLC) |
CaM kinase III (eEF-2 kinase) inhibitor
Chemical Name : | 7-Amino-1-cyclopropyl-3-ethyl-1,2,3,4-tetrahydro-2,4-dioxopyrido[2,3-d]pyrimidine-6-carboxamide |
Purity : | ≥98% (HPLC) |
Prototypical PI 3-kinase inhibitor; also inhibits other kinases
Chemical Name : | 2-(4-Morpholinyl)-8-phenyl-4H-1-benzopyran-4-one hydrochloride |
Purity : | ≥99% (HPLC) |
Non-selective PI 3-kinase inhibitor
Chemical Name : | 2-(3,4-Dihydroxyphenyl)-3,5,7-trihydroxy-4H-1-benzopyran-4-one |
Purity : | ≥98% (HPLC) |
Potent, reversible EGFR tyrosine kinase inhibitor
Chemical Name : | N-(3-Ethynylphenyl)-6,7-bis(2-methoxyethoxy)-4-quinazolinamine hydrochloride |
Purity : | ≥98% (HPLC) |
Potent adenosine kinase inhibitor; also inhibits nucleoside transporters and a range of other kinases
Chemical Name : | 5-Iodo-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine |
Purity : | ≥97% (HPLC) |
Potent, selective Src family kinase inhibitor
Chemical Name : | 3-(4-chlorophenyl) 1-(1,1-dimethylethyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine |
Purity : | ≥99% (HPLC) |
Integrated stress response (ISR) inhibitor
Chemical Name : | N,N'-trans-1,4-cyclohexanediylbis[2-(4-chlorophenoxy)acetamide] |
Purity : | ≥99% (HPLC) |
Potent and selective ATM kinase inhibitor
Chemical Name : | 2-(4-Morpholinyl)-6-(1-thianthrenyl)-4H-pyran-4-one |
Purity : | ≥98% (HPLC) |
Potent, selective c-Raf1 kinase inhibitor
Chemical Name : | 3-(3,5-Dibromo-4-hydroxy-benzylidene)-5-iodo-1,3-dihydro-indol-2-one |
Purity : | ≥98% (HPLC) |
High affinity and selective p38 kinase inhibitor
Alternate Names : | Doramapimod |
Chemical Name : | N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea |
Purity : | ≥98% (HPLC) |