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60 results for "neural stem cells" in Products

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60 results for "neural stem cells" in Products

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Selective ROCK inhibitor; inhibits ROCK1 (p160 ROCK) and ROCK2; stem cell freezing (cryopreservation) media component

Alternate Names : y27632, Y-27632 2HCl, ROCK inhibitor, ROCK1 inhibitor
Chemical Name : trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity : ≥98% (HPLC)
ROCK inhibition by Y-27632 and immunostaining of skeletal myogenic differentiation of MESP1+ mesoderm,
(2)

Y-27632 synthesized to cGMP guidelines

Chemical Name : trans-4-[(1R)-1-Aminoethyl]-N-4-pyridinylcyclohexanecarboxamide dihydrochloride
Purity : ≥99%
Y-27632 synthesized to cGMP guidelines

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name : 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity : ≥99% (HPLC)
dopaminergic neurons derived from hiPSCs using SB 431542
(2)
Catalog #: TB1614-GMP

SB 431542 synthesized to cGMP guidelines

Chemical Name : 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity : ≥99%
SB 431542 synthesized to cGMP guidelines

Highly selective GSK-3 inhibitor; acts as Wnt activator

Alternate Names : CHIR99021, CT99021
Chemical Name : 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity : ≥98% (HPLC)
Cardiomyocyte derived from human induced pluripotent stem cells (hiPSCs) using CHIR 99021.
(2)

CHIR 99021 synthesized to cGMP guidelines

Chemical Name : 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity : ≥99%
CHIR 99021 synthesized to cGMP guidelines

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name : 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Purity : ≥98% (HPLC)
Selective inhibitor of TGF-βRI, ALK4 and ALK7

Gamma γ-secretase inhibitor; induces neuronal differentiation; blocks Notch signaling

Chemical Name : (2S)-N-[(3,5-Difluorophenyl)acetyl]-L-alanyl-2-phenyl]glycine 1,1-dimethylethyl ester
Purity : ≥99% (HPLC)
Using DAPT to differentiate hiPSCs into dopaminergic neurons
(2)

Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs

Chemical Name : 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity : ≥98% (HPLC)
Application of LDN 193189 in motor neurons differentiated from iPSCs
(2)

γ-secretase inhibitor; induces neuronal differentiation

Alternate Names : γ-Secretase Inhibitor XXI
Chemical Name : N-[(1S)-2-[[(3S)-2,3-Dihydro-1-methyl-2-oxo-5-phenyl-1H-1,4-benzodiazepin-3-yl]amino]-1-methyl-2-oxoethyl]-3,5-difluorobenzeneacetamide
Purity : ≥98% (HPLC)
γ-secretase inhibitor; induces neuronal differentiation
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