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Visit us at Booth #2014  | November 11-15th | Walter E. Washington Convention Center | Washington, D.C.

Bio-Techne is committed to enabling the progress of neuroscience research and discovery by assuring the scientific quality of our reagents, assays, instruments, and technical support. We offer products for spatial mapping and phenotyping, neural cell imaging and detection, neural cell culture, modulating neural activity, and biomarker quantitation and validation. Together, we elevate science to the next level of possibility.

Poster Presentations

Investigating Neuroinflammation in the Human Brain Tumor Microenvironment Using a Novel RNA-protein Co-detection Assay

Session Title:  Single-Cell Approaches for Understanding Brain Structure and Function 

Debia Wakhloo, PhDApplication Scientist, Bio-Techne

Tuesday | November 14th | 1:00 - 2:00 PM 
Session PSTR442 | Abstract 8982

Debia Wakhloo, Ph.D.

A Reproducible and Quantitative Capillary Electrophoresis Immunoassay for eNOS Protein Expression Measurements Directly in Human Brain Tissue Homogenates 

Session Title:   Molecular and Cellular Techniques for Discovery and Therapeutics  

Monica MiliciField Applications Scientist, Bio-Techne

Monday | November 13th | 1:00 - 2:00 PM 
Session PSTR310 | Abstract 13268 

Monica Milici

Simultaneous Spatial Evaluation of IDH1, EGFR, IGF1R, and Ki67 Biomarkers in Glioblastoma

Session Title:  Molecular and Cellular Techniques for Discovery and Therapeutics 

Alex Kalyuzhny, PhD, Antibody Development Manager, IHC, Bio-Techne

Monday | November 13th | 2:00 - 3:00 PM
Session PSTR310 | Abstract 5390

Alexander Kalyuzhny, PhD

A Microfluidic Strategy for the Analysis of Blood Glial Fibrillary Acidic Protein (GFAP) Across Neurodegenerative Disorders 

Session Title:  Alzheimer's Disease: Biomarkers and Risk Factors  

Yoav Noam, PhD, Simple Plex Development Manager, Bio-Techne

Monday | November 13th | 8:00 - 9:00 AM
Session PSTR198 | Abstract 7473

Yoav Noam, PhD

Spatial Mapping and Phenotyping

RNAscope™ Plus smRNA RNA Assay

True Multiomic assay enabling detection of miRNAs/siRNA/ASOs with RNA and proteins.  

Combining proprietary RNAscope and miRNAscope ISH technologies to quantify changes in gene expression and cellular function in response to the introduction of regulatory RNAs, essential for optimization of therapeutic efficacy and safety. RNAscope Plus smRNA-RNA assay allows simultaneous detection of 1 smRNA and up to 2/3 RNA targets along with a protein marker within a single sample. 

RNAscope™ Plus

Neural Cell Imaging and Detection

Antibodies Visucyte HRP Illustration

Coming Soon! VisUCyte™ HRP Polymer Detection Kits

VisUCyte™ HRP Polymer Detection Kits are a biotin-free IHC detection reagent kit which overcome problems of avidin-biotin detection chemistry. These kits are suited for both basic and clinical research, and HRP polymer conjugated secondary antibodies can be used for manual protocols as well as for tissue autostainers.

ICC IHC Antibodies Data Image

Custom Conjugation of IHC/ICC Validated Antibodies

Our IHC and ICC validated primary antibodies can be conjugated directly to fluorochromes like Alexa Fluor® 488, Alexa Fluor® 647, PE, FITC and more. Direct conjugation allows for easier multiplexing to simplify your spatial biology experiments.

PROTAC degrader molecule in complex with an E3 ligase and the target protein

TR-FRET and FP Assay Reagents

Study target engagement for drug discovery, protein-protein interactions, enzyme kinetics, and receptor-ligand binding. 

CoraFluor™ TR-FRET target engagement assay

CoraFluor™ 1, amine reactive

Terbium cryptate FRET donor for TR-FRET assay development, including target engagement and ternary complex assays. 

Suitable for labeling biomolecules, including antibodies, nanobodies, proteins and peptides. It is exceptionally bright, providing unmatched assay sensitivity and stability in biological media over other commercially available TR-FRET donors. 

Biomarker Quantitation and Validation

Immunoassay Kits -GNR

New Immunoassay Kits

Simple Plex offers a menu of over 250 fully validated assays run with Ella, including a rapidly expanding neuro selection including GFAP, Amyloid Beta 1-40, Amyloid Beta 1-42, NF-L, NF-H, and Neurogranin. Our assays provide results you can trust in less than 90 minutes, have built in standard curves, and are developed to be extremely sensitive, detecting low endogenous levels in serum, plasma, and CSF samples. 

Jess Instrument Simple Western

Western Blot Meets ELISA

Get quantitative reproducible data from cell, viral, and tissue lysates in about 3 hours. Western Blot-like data with reproducibility that will get you published faster. 

Modulate Neural Activity

Neurons firing action potentials

Fluorescent Metal Ion Indicators

For the detection of ionic gradients in live cells.

Measure ion gradients in real-time using flow cytometry or fluorescent imaging, can also be used in high throughput screening assays. A highly selective and sensitive tool to help you identify novel compounds that modulate ion channel activity, understand drug mechanism of action and monitor ion flux in live cells. 

Neural Cell Culture

Organoids FrontImg  V2 480x480

Organoid and 3-D Cell Culture Products

Optimize your organoid culture conditions with our wide selection of Cultrex BMEs, cytokines, small molecules, media, and media supplements, which are designed to provide superior performance and ensure culture consistency. Along with our products for culturing organoids, we also offer antibodies and RNAscope™ in situ hybridization assays for detecting lineage-specific markers. 

stem cells in culture at Bio-Techne

Optimize Your Neural Stem Cell Cultures

Minimize variability in your culture conditions and ensure robust expansion and differentiation with our neural stem cell culture reagents. Our Cultrex BME/ECM products, media, proteins, and small molecules are designed to provide superior performance and lot-to-lot consistency, so you can be confident that your results will be reproducible from one experiment to the next.

Namocell Pala Instrument

Pala Single Cell Dispenser

The fast, gentle, and easy Pala Single Cell Dispenser is here to make the tedious and low efficiency limiting dilution and harsh FACS sorting that damages your stem cells a thing of a past. With walk-up usability and rapid single cell deposition, you can have your stem cells precisely dispensed in 96- or 384-well plate in as little as under 10 minutes. The ultralow sorting pressure will leave your cells' health with better clonal growth.  

GMP ExCellerate iPSC Expansion Medium

Now Available! ExCellerate™ GMP iPSC Expansion Medium

Completely Animal-Free, All-in-One Formulation 

Advance your stem cell program into clinical manufacturing with ease. Our new medium enables robust and reproducible feeder-free human iPSC expansion and maintenance. It doesn’t require supplementation, so it simplifies your media prep too. 

IL-2 protein ribbon structure

Animal-Free Preclinical Proteins

R&D Systems™ Animal-free Preclinical Proteins are produced in dedicated animal-free laboratories and are manufactured using the same systems as our GMP-grade Proteins, ensuring a seamless transition from preclinical research into clinical manufacturing. Start testing! Animal-Free Protein samples are now available. 

GMP Proteins IL-2 Bottle

GMP Proteins for Transition to Clinical Manufacturing

Transition your program to GMP with our new growth factors that support neuronal growth and differentiation. These proteins have equivalent bioactivity as our preclinical versions. They’re the next logical step following our neuroscience bundle of ECM components, media, proteins, small molecules, and antibodies. 

  • GMP Activin A* 
  • GMP BDNF * 
  • GMP Flt-3 Ligand 
  • GMP Shh * 

*Coming Soon!