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Precision Multiplexing Made Simple with Ella

A Benchtop Automated ELISA Platform for Consistent Biomarker Detection

Ella’s cartridges contain fully validated assays powered by R&D Systems to deliver fast, reproducible data with no manual steps. Advanced microfluidic circuitry performs every step of the assay process to help eliminate variability and minimize user error.

Customizable cartridges can assay up to 8 analytes simultaneously in less than 90 minutes and require only 25µL of sample. All assays are fully validated, highly sensitive, and feature up to 4 logs of dynamic range. Discover the confidence and convenience Ella can bring to your lab.

Gain a Performance Advantage with Ella

Watch as Ella customers share how this automated ELISA platform helps them get consistent, reproducible data with no manual steps. Listen to customers explain how the platform’s hands-free workflow helps them reduce user error, eliminate cross-reactivity, and accelerate time to results.

Hear from Ella Users

Rigorously Controlled for Accurate Biomarker Detection

Ella instrument - with cartridge loaded

Meet Ella. Your Automated ELISA.

Ella is your immunoassay problem-solver. Everything is pre-loaded onto the Ella cartridge. Simply add sample and buffers, load the cartridge into the instrument, and walk away. Then watch Ella give you fully analyzed answers in less than 90 minutes. 

Cygnus cartridge for Ella instrument

Explore Ella Assays

Ella assays powered by R&D Systems are available in a variety of flexible cartridge formats. From single analyte assays to custom panels, there’s an Ella cartridge that meets your needs. Choose from a menu of more than 200 fully validated assays.

icon illustrating the various costs related to ELISA

How much is your ELISA costing you?

Discover how the high-precision Ella platform completely changes the cost-benefit dynamics of traditional ELISAs. Ella's hands-free automated workflow reduces user error while lowering your cost per data point. Fast onboarding with fewer mistakes helps maximize the return on your immunoassay investment.

Accelerate Discovery with Rapid Development and Reproducible Results

Automated ELISA with Ella

Fast and Efficient

  • Reduce manual steps by up to 80%.
  • Save time and maximize data with preloaded standard curves.
  • Get validated assay data in less than 90 minutes.

“Simple Plex assays on Ella gave us speed and efficiency so we could complete our assays quickly, and the high quality of the data meant that we could easily see differences between disease state samples and controls. Plus, sample preparation was so simple it reduced chances of errors significantly.” 

Paulomi Aldo, Research Associate and Reproductive Sciences Core Manager, Yale University

Automated ELISA multi-site data showing high reproducibility of assay.

Highly Reproducible

  • Less than 7% variability across assay lots.
  • Reduce human error and variability with hand-free automation.
  • Get consistent, reproducible answers across multiple users and sites. 

“A major advantage of Ella is that it’s very easy to use with virtually no maintenance, and it’s really fast. Simply dilute your sample and you’re ready to go—without the need for manual preparations that can take time and add user variability.” 

— Dr. Jesús F Bermejo-Martín, Principal Investigator, Hospital Universitario Río Hortega de Valladolid

AAV viral titer assays on automated ELISA system Ella

Accurate and Reliable

  • Generate triplicate data with only 25 µL of sample volume.
  • Eliminate cross-reactivity by detecting each analyte in separate parallel channels.
  • Extensive validation using FDA guidelines.  

"Ella allows for reproducible sample data with minimal sample input. The lower volume usage allows for the expansion of research into novel areas of angiogenesis and inflammation as they pertain to many forms of cancer."

— Andrew Nixon, Ph.D., M.B.A., Associate Professor, Medicine & Director, Duke University

Fast Setup and On-the-Fly Adjustments

All the assay steps on Ella are highly automated thanks to the microfluidic cartridge—everything is preloaded, even the calibration curve.

  1. Pipette your diluted samples onto the cartridge and add wash buffer.
  2. Place cartridge into the Ella instrument.
  3. Press run and get analyzed results in just over an hour.
  4. Save time and labor costs with easy setup.
  5. Get the same answers across multiple users and multiple sites.

Optimize Your Data Points

Ella Cartridges Card 350x210 - white

Large Menu

Generate the data you need quickly and efficiently with customizable assay panels to interrogate multiple targets in one cartridge.

Talk to your local Ella immunoassay specialist about designing the perfect assay panel.

Ella Cart Chart Card

Flexible Cartridge Formats

Select the right format for your research needs.

Mix and match analytes and create a custom panel. Or maximize throughput for a single analyte with the 72-sample cartridge.

Accurate Biomarker Detection from a Brand You Can Trust

Cancer Cell


Validate cancer biomarkers faster and with higher throughput. Lower volume sample usage with Ella assays allows for research expansion into novel target areas.

Dendritic Immune Cell


Standardize your immunoassay for immune reactivity and inflammation research. Monitor concentrations of key biomarkers in near real-time.

Immune Cell

Immune Profiling

Investigate and quantify immune responses and get your results in 90 minutes. Hands-free workflow minimizes variability and helps ensure accurate, reproducible results.   

Neuroscience Biomarker Multiplex Assay


Measure key neuroscience biomarkers using just 25 μL of sample. Detect and measure endogenous levels of proteins across a wider and more sensitive detection range.

Immune Cell Therapy Image

Cell Therapy

Obtain critical cell characterization data on your product. Iterate your development process faster and automatically obtain triplicate results for every sample.


Bioprocess Workflow Assays

Boost your throughput with a hands-free workflow for process impurity testing. Get reproducible results across multiple users and multiple sites.


Simple Plex AAV application note

Fast and Accurate Viral Titration

  • Fast and reproducible AAV vector quantification
  • Linear correlation with the industry-leading PROGEN ELISA
  • Larger dynamic range than ELISA.
Simple Plex automated ELISAs advantages over plate based ELISAs

Precision Multiplexing with Fast Results

  • Multiplex results in less than 90 minutes
  • No cross-reactivity with separate channels
  • Hands-free assay setup
  • Built-in standard curve
Cover of the Cell Killing App Note

Quantify Secreted T Cell Activation Markers

  • Rapid and precise quantification of T Cell activation markers
  • Data in less than 90 minutes
  • Ready-to-use ELISA kits are also available
Endonuclease App Note

Rapid Endonuclease (Benzonase®) Quantification

  • Fast and reproducible endonuclease quantification
  • Detects both Benzonase® and Denarase®

Benzonase is a registered trademark of Merck KGaA Corp.