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Featured Small Molecule Product Types

Tocriscreen plate and molecules for compound libraries page

Compound Libraries

The Tocriscreen™ range of bioactive compound libraries are collections of small molecules designed for use in assays for target validation, tool compound identification, receptor de-orphanization and assay development. The range includes libraries covering a diverse range of research areas and targets, as well as focused libraries for specific targets and drug repurposing.

Targeted protein degradation

Protein Degraders

Small molecule protein Degraders (e.g. PROTAC® Degraders) are used to achieve selective knock-down of target proteins by harnessing the ubiquitin-proteasome system and without the requirement for genetic modification of cells. Bio-Techne provides a wide range of Protein Degraders and negative controls to help you investigate your target of interest.

LNP Teaser FrontImg

Lipid Nanoparticles (LNPs)

LNPs are non-viral drug delivery systems for a wide range of pharmaceutical cargoes, including small molecules, peptides, and nucleic acids, intended for delivery into target cells in vitro or in vivo. Bio-Techne offers all the essential components to help further your LNP research.

Fluorescent probes and dyes

Fluorescent Dyes and Probes

Fluorescent dyes and probes allow visualization of intracellular structures and individual proteins, and determination of cell types, in live and fixed cells with high sensitivity and selectivity. Our range includes Janelia Fluor® Dyes, cytoskeletal and microtubule probes as well as innovative probes for imaging bacteria. 

Stem Cell Cluster

CEPT Cocktail

Improve the viability of PSCs with CEPT Cocktail. A combination of 4 small molecules, the CEPT Cocktail enhances cell survival in a wide range of experimental procedures, including routine long-term passaging, single-cell cloning, gene editing, differentiation and cryopreservation of PSCs.

Neurons firing action potentials


Chemogenetic compounds, such as DREADD ligands and PSEMs, act at genetically modified GPCRs and ion channels, respectively. They enable control of neuronal activity, and investigation of downstream signaling pathways, by initiating a signal cascade from a GPCR or opening of an ion channel pore. 

TR-FRET and FP Assay Reagents


TR-FRET (Time-Resolved Fluorescence Resonance Energy Transfer) and FP (Fluorescence Polarization) assays are widely used in biology and drug discovery to study target engagement. Discover our range of fluorescent probes, including CoraFluor™ terbium cryptate FRET donors, suitable for exploring ligand binding in TR-FRET and FP assays.

New Small Molecules & Peptides

CoraFluor™ 1, amine reactive | 7920

  • Terbium cryptate FRET donor for TR-FRET assay development
  • Compatible with acceptor dyes such as FAM, TMR, Cyanine 5, SE
  • Exceptionally bright

CELT-133 | 7952

  • Fluorescent selective hα1A adrenergic receptor antagonist
  • Suitable for TR-FRET assays, confocal microscopy, high content screening

TM2 TEAD inhibitor | 7917

  • Potent and reversible TEAD inhibitor
  • Inhibits TEAD-YAP association and transcriptional activity
  • Exhibits antiproliferation effects in YAP-dependent cancer cells

Browse Products by Pharmacology

Selected Small Molecule Resources

Epigenetics in Cancer Product Guide

Epigenetics in Cancer Research Product Guide

Our Epigenetics in Cancer Product Guide reviews some of the main areas in cancer epigenetics research and highlights products that can be used for the main epigenetic targets.


Stem cell research guide

Stem Cell Research Product Guide

Our Stem Cell Product Guide provides a background to the use of small molecules in stem cell research and the development of cell therapies. The application of small molecules in stem cell differentiation, maintenance, and reprogramming is discussed. 

Alzheimer Disease Brochure

Alzheimer's Disease Research Product Guide

In this guide the molecular mechanisms behind the pathophysiology of Alzheimer’s disease are outlined including the amyloid cascade, tau and cholinergic hypotheses and mitochondrial dysfunction. Small molecules for research in the field are highlighted.  


Use our Molarity Calculator to plan your experiment

Molarity Calculator

Calculate the mass, volume or molar concentration required for a solution.

Use our Dilution Calculator to plan your experiment

Dilution Calculator

Calculate the dilution required to prepare a stock solution.

Use our Reconstitution Calculator to plan your experiment

Reconstitution Calculator

Calculate the volume of solvent required to reconstitute the contents of your vial.

Background Information

PROTAC® is a registered trademark of Arvinas Operations, Inc., and is used under license.