Tocriscreen 2.0 Micro

Name: Tocriscreen 2.0 Micro
Brand: Tocris Bioscience
SKU: 7152

Catalog # 7152 | Tocris Bioscience a Bio-Techne Brand

Bioactive compound library for high-throughput screening, high-content screening and chemical biology applications; comprised of 1280 biologically active compounds (15 μL 10 mM DMSO solutions)

Key Product Details

Description:

Bioactive compound library for high-throughput screening, high-content screening and chemical biology applications; comprised of 1280 biologically active compounds (15 μL 10 mM DMSO solutions)

Key Format Details:

96-well microplate format with peelable foil seal
Compounds arranged 80 per plate with 16 plates per library
Pre-dissolved in DMSO

Many compounds are exclusive to Tocris
Unique library with low overlap
Full chemical and biological data available
Exceptional purity

Note: Due to the small volume of this product, please ensure the liquid has settled to the bottom of the well before removing the foil seal.

This library is supplied in a Corning Microplate; recommended centrifugation for this plate is 1000g or less

Target Classes Covered by the Tocriscreen 2.0 Compound Library

The Tocriscreen 2.0 Compound Library contains bioactive compounds covering a diverse range of molecular targets; 7-TM receptors (GPCRs; 27%), non-kinase enzymes (21%), kinases including enzyme-linked receptors (20%), ion channels (13%), cell biology targets (9%), nuclear receptors (6%), and transporters and other pharmacological targets (5%).

View Full Technical Details for Tocriscreen 2.0 Micro

Technical Data
Citations (9) / Reviews

Product Description for Tocriscreen 2.0 Micro

Tocriscreen 2.0 Micro is a a library of 1280 biologically active compounds from the Tocris catalog. The compounds within this bioactive compound library cover a wide range of pharmacological targets and research areas. Compounds are supplied pre-dissolved in 15 μL 10 mM DMSO solutions. A larger volume is available as Tocriscreen 2.0 Mini (Cat. No. 7151).

This library replaces the Tocriscreen Plus Micro (Cat. No. 6455).

For more information on the Tocriscreen 2.0 Compound Libraries, please download our informative flyer.

If this library does not suit your needs, please submit your requirements through our Tocriscreen PRO custom compound library service.

Request Compound List

A list of the compounds available in the Tocriscreen 2.0 Micro can be requested in Excel or SD format via our Tocriscreen & Custom Library Inquiries form.

Technical Data for Tocriscreen 2.0 Micro

Storage	Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.

Tocris products are intended for laboratory research use only, unless stated otherwise.

References for Tocriscreen 2.0 Micro

References are publications that support the biological activity of the product.

Li Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell. 2015 PMID: 26253201
Yu Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell 2015 PMID: 25658371
Li Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Research. 2011 PMID: 20956998
Beacham Cell-based potassium ion channel screening using the FluxOR^TM assay. J.Biomol.Screen. 2010 PMID: 20208034
Hattori Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proc.Natl.Acad.Sci.USA. 2010 PMID: 20142487

Citations for Tocriscreen 2.0 Micro (9)

Showing 1 - 9 of 9 citations Showing All

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Citations are publications that use Bio-Techne products. Selected citations for Tocriscreen 2.0 Micro include:

Pals et al. (2023) A quenched size-expanded nucleotide reports activity of the leukemia biomarker Terminal deoxynucleotidyl Transferase (TdT). Angew.Chem.Int.Ed.Engl.. 62:e202302796
PMID: 36880583
Parijat et al. (2023) Discovery of novel cardiac troponin activators using fluorescence polarization-based high throughput screening assays. Sci.Rep.. 13:5216
PMID: 36997544
Benmerah et al. (2023) Repurposing small molecules for nephronophthisis and related renal ciliopathies. Kidney Int.. 104:245
PMID: 37244473
Kim et al. (2023) Advanced human iPSC-based preclinical model for Parkinson�s disease with optogenetic alpha-synuclein aggregation. Cell Stem Cell. 30:973
PMID: 37339636
Gull et al. (2022) Screening of chemical libraries using xenopus embryos and tadpoles for phenotypic drug discovery. Cold Spring Harb.Protoc.. 2022;
PMID: 36180216
Abduljalil et al. (2022) Screening the Tocriscreen^TM bioactive compound library in search for inhibitors of Candida biofilm formation. APMIS. 130:568
PMID: 3579108
Lee & Jeong et al. (2022) NMDA Receptor Antagonists Degrade Lipofuscin via Autophagy in Human Retinal Pigment Epithelial Cells Medicina (Kaunas). 58:1129
PMID: 36013596
Forfar et al. (2022) Identification of a novel specific small-molecule melanocortin-2-receptor antagonist. Endocr Connect. 11:e220338
PMID: 36515667
Liu et al. (2020) Ultrasensitive small molecule fluorogenic probe for human heparanase. Chem Sci. 12:239
PMID: 34163592

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