Y-27632 dihydrochloride

Citations are publications that use Bio-Techne products. Selected citations for Y-27632 dihydrochloride include:

• Schafer et al. (2023) An in vivo neuroimmune organoid model to study human microglia phenotypes. Cell. 186:2111
  PMID: 37172564
• Zhan et al. (2022) Pancreatic islet cryopreservation by vitrification achieves high viability, function, recovery and clinical scalability for transplantation. Nat.Med.. 28:798
  PMID: 35288694
• Surendran et al. (2022) An improved protocol for generation and characterization of human-induced pluripotent stem cell-derived retinal pigment epithelium cells STAR Protoc. 3:101803
  PMID: 36386870
• Kim et al. (2021) Biphasic activation of WNT signaling facilitates the derivation of midbrain dopamine neurons from hESCs for translational use. Cell Stem Cell. 28:343
  PMID: 33545081
• Piao et al. (2021) Preclinical Efficacy and Safety of a Human Embryonic Stem Cell-Derived Midbrain Dopamine Progenitor Product, MSK-DA01 Cell Stem Cell. 28:217
  PMID: 33545080
• Leibel et al. (2020) Generation of Complete Multi-Cell Type Lung Organoids From Human Embryonic and Patient-Specific Induced Pluripotent Stem Cells for Infectious Disease Modeling and Therapeutics Validation Curr Protoc Stem Cell Biol. 54:e118
  PMID: 32640120
• Panciera et al. (2020) Reprogramming normal cells into tumour precursors requires ECM stiffness and oncogene-mediated changes of cell mechanical properties. Nat Mater. 19:797
  PMID: 32066931
• Yin et al. (2019) Chemical conversion of human fetal astrocytes into neurons through modulation of multiple signaling pathways. Stem Cell Reports. 12:488
  PMID: 30745031
• Delpiano et al. (2019) Esomeprazole Increases Airway Surface Liquid pH in Primary Cystic Fibrosis Epithelial Cells. Front Pharmacol. 9:1462
  PMID: 30618754
• Wang et al. (2019) Efficient generation of human primordial germ cell-like cells from pluripotent stem cells in a methylcellulose-based 3D system at large scale. PeerJ. 6:e6143
  PMID: 30643676
• Lang et al. (2019) Single-Cell Sequencing of iPSC-Da Neurons Reconstructs Disease Progression and Identifies HDAC4 as a Regulator of Parkinson Cell Phenotypes. Cell Stem Cell. 24:93
  PMID: 30503143
• Georgouli et al. (2019) Regional Activation of Myosin II in Cancer Cells Drives Tumor Progression via a Secretory Cross-Talk with the Immune Microenvironment. Cell. 176:757
  PMID: 30712866
• Larraufie et al. (2019) Important Role of the GLP-1 Axis for Glucose Homeostasis after Bariatric Surgery. Cell Rep. 26:1399
  PMID: 30726726
• Vila et al. (2019) Quantification of human neuromuscular function through optogenetics. Theranostics. 9:1232
  PMID: 30867827
• Zhuang et al. (2019) The novel function of tumor protein D54 in regulating pyruvate dehydrogenase and MetF. cytotoxicity in breast cancer. Cancer Metab. 7:1
  PMID: 30697423
• Martin-Gallausiaux et al. (2019) Butyrate Produced by Commensal Bacteria Down-Regulates Indolamine 2,3-Dioxygenase 1 (IDO-1) Expression via a Dual Mechanism in Human Intestinal Epithelial Cells. Front Immunol. 9:2838
  PMID: 30619249
• Ervin et al. (2019) Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14. Stem Cell Res Ther. 10:43
  PMID: 30678718
• Gao et al. (2019) Establishment of porcine and human expanded potential stem cells. Nat Cell Biol. 21:687
  PMID: 31160711
• Park et al. (2019) Dual stem cell therapy synergistically improves cardiac function and vascular regeneration following myocardial infarction. Nat Commun. 10:3123
  PMID: 31311935
• Genga et al. (2019) Single-Cell RNA-Sequencing-Based CRISPRi Screening Resolves Molecular Drivers of Early Human Endoderm Development. Cell Rep. 27:708
  PMID: 30995470
• Rhee et al. (2019) An Autaptic Culture System for Standardized Analyses of iPSC-Derived Human Neurons. Cell Rep. 27:2212
  PMID: 31091457
• Meijer et al. (2019) A Single-Cell Model for Synaptic Transmission and Plasticity in Human iPSC-Derived Neurons. Cell Rep. 27:2199
  PMID: 31091456
• Hackland et al. (2019) FGF Modulates the Axial Identity of Trunk hPSC-Derived Neural Crest but Not the Cranial-Trunk Decision. Stem Cell Reports. 12:920
  PMID: 31091435
• Celano et al. (2019) Identification of Kinases Responsible for p53-Dependent Autophagy. iScience. 15:109
  PMID: 31048145
• Regier et al. (2019) User-defined morphogen patterning for directing human cell fate stratification. Sci Rep. 9:6433
  PMID: 31015521
• Ng-Blichfeldt et al. (2019) TGF-β activation impairs fibroblast ability to support adult lung epithelial progenitor cell organoid formation. Am J Physiol Lung Cell Mol Physiol. 2019;
  PMID: 30969812
• Mair et al. (2019) Essential Gene Profiles for Human Pluripotent Stem Cells Identify Uncharacterized Genes and Substrate Dependencies. Cell Rep. 27:599
  PMID: 30970261
• Nguyen et al. (2019) Constructing an Isogenic 3D Human Nephrogenic Progenitor Cell Model Composed of Endothelial, Mesenchymal, and SIX2-Positive Renal Progenitor Cells. Stem Cells Int. 2019:3298432
  PMID: 31191670
• Ranganathan et al. (2019) Evaluating Shigella flexneri pathogenesis in the human enteroid model. Infect Immun. 87
  PMID: 30642900
• Bertero et al. (2019) Dynamics of genome reorganization during human cardiogenesis reveal an RBM20-dependent splicing factory. Nat Commun. 10:1538
  PMID: 30948719
• Chen et al. (2019) A versatile polypharmacology platform promotes cytoprotection and viability of human pluripotent and differentiated cells. Nat.Methods. 18:528
  PMID: 33941937
• Aureille et al. (2019) Nuclear envelope deformation controls cell cycle progression in response to mechanical force. EMBO Rep. 20:e48084
  PMID: 31368207
• Bryant et al. (2019) Repurposed quinacrine synergizes with CIS. reducing the effective dose required for treatment of head and neck squamous cell carcinoma. Oncotarget. 10:5229
  PMID: 31497252
• Schwedhelm et al. (2019) Automated real-time monitoring of human pluripotent stem cell aggregation in stirred tank reactors. Sci Rep. 9:12297
  PMID: 31444389
• Crowell et al. (2019) Expansion of Luminal Progenitor Cells in the Aging Mouse and Human Prostate. Cell Rep. 28:1499
  PMID: 31390564
• Sharma et al. (2019) Exosomes regulate neurogenesis and circuit assembly. Proc Natl Acad Sci U S A. 116:16086
  PMID: 31320591
• Vattulainen et al. (2019) Modulation of Wnt/BMP pathways during corneal differentiation of hPSC maintains ABCG2-positive LSC population that demonstrates increased regenerative potential. Stem Cell Res Ther. 10:236
  PMID: 31383008
• Wang et al. (2019) Protective effects of oxymatrine against DSS-induced acute intestinal inflammation in mice via blocking the RhoA/ROCK signaling pathway. Biosci Rep. 39
  PMID: 31262973
• Hladik et al. (2019) Long-term culture of mesenchymal stem cells impairs ATM-dependent recognition of DNA breaks and increases genetic instability. Stem Cell Res Ther. 10:218
  PMID: 31358047
• Wilke et al. (2019) A Stem-Cell-Derived Platform Enables Complete Cryptosporidium Development In Vitro and Genetic Tractability. Cell Host Microbe. 26:123
  PMID: 31231046
• Rehbach et al. (2019) Multiparametric rapid screening of neuronal process pathology for drug target identification in HSP patient-specific neurons. Sci Rep. 9:9615
  PMID: 31270336
• Lee et al. (2019) Entosis Controls a Developmental Cell Clearance in C. elegans. Cell Rep. 26:3212
  PMID: 30893595
• Montel-Hagen et al. (2019) Organoid-Induced Differentiation of Conventional T Cells from Human Pluripotent Stem Cells. Cell Stem Cell. 24:376
  PMID: 30661959
• Li et al. (2019) A Non-canonical Pathway with Potential for Safer Modulation of Transforming Growth Factor-β1 in Steroid-Resistant Airway Diseases. iScience. 12:232
  PMID: 30711747
• Maguire et al. (2019) Highly Efficient CRISPR-Cas9-Mediated Genome Editing in Human Pluripotent Stem Cells. Curr Protoc Stem Cell Biol. 48:e64
  PMID: 30358158
• Frith and Tsakiridis (2019) Efficient Generation of Trunk Neural Crest and Sympathetic Neurons from Human Pluripotent Stem Cells Via a Neuromesodermal Axial Progenitor Intermediate. Curr Protoc Stem Cell Biol. :e81
  PMID: 30688409
• Duman et al. (2019) The adhesion-GPCR BAI1 shapes dendritic arbors via Bcr-mediated RhoA activation causing late growth arrest. Elife. 8:e47566
  PMID: 31461398
• Bantounas et al. (2018) Generation of functioning nephrons by implanting human pluripotent stem cell-derived kidney progenitors. Stem Cell Reports. 10:766
  PMID: 29429961
• Magro-Lopez et al. (2018) Effects of lung and airway epithelial maturation cocktail on the structure of lung bud organoids. Stem Cell Res.Ther.. 9:186
  PMID: 29996941
• Sommer et al. (2018) Th17 lymphocytes induce neuronal cell death in a human iPSC-based model of Parkinson's disease. Cell Stem Cell.. 23:123
  PMID: 29979986
• Wong et al. (2018) α-Tubulin Acetyltransferase Is a Novel Target Mediating Neurite Growth Inhibitory Effects of Chondroitin Sulfate Proteoglycans and Myelin-Associated Glycoprotein. Eneuro. 5
  PMID: 29497702
• Ho et al. (2018) Lysophosphatidic Acid Induces ECM Production via Activation of the Mechanosensitive YAP/TAZ Transcriptional Pathway in Trabecular Meshwork Cells. Invest Ophthalmol Vis Sci. 59:1969
  PMID: 29677358
• Sima et al. (2018) Neural stem cells for disease modeling and evaluation of therapeutics for infantile (CLN1/PPT1) and late infantile (CLN2/TPP1) neuronal ceroid lipofuscinoses. Orphanet J Rare Dis. 13:54
  PMID: 29631617
• Medelnik et al. (2018) Signaling-Dependent Control of Apical Membrane Size and Self-Renewal in Rosette-Stage Human Neuroepithelial Stem Cells. Stem Cell Reports. 10:1751
  PMID: 29779899
• Levardon et al. (2018) Expansion of Airway Basal Cells and Generation of Polarized Epithelium. Bio Protoc. 8
  PMID: 30009215
• McHugh et al. (2018) Preclinical comparison of proteasome and ubiquitin E1 enzyme inhibitors in cutaneous squamous cell carcinoma: the identification of mechanisms of differential sensitivity. Oncotarget. 9:20265
  PMID: 29755650
• Hepburn et al. (2018) Targeting the spliceosome for cutaneous squamous cell carcinoma therapy: a role for c-MYC and wild-type p53 in determining the degree of tumour selectivity. Oncotarget. 9:23029
  PMID: 29796170
• Vu et al. (2018) Neural stem cells for disease modeling and evaluation of therapeutics for Tay-Sachs disease. Orphanet J Rare Dis. 13:152
  PMID: 30220252
• Tidball et al. (2018) Generating Loss-of-function iPSC Lines with Combined CRISPR Indel Formation and Reprogramming from Human Fibroblasts. Bio Protoc. 8
  PMID: 30320153
• Ng-Blichfeldt et al. (2018) Retinoic acid signaling balances adult distal lung epithelial progenitor cell growth and differentiation. EBioMedicine. 36:461
  PMID: 30236449
• McKown et al. (2018) Impaired adhesion of induced pluripotent stem cell-derived cardiac progenitor cells (iPSC-CPCs) to isolated extracellular matrix from failing hearts. Heliyon. 4:e00870
  PMID: 30364772
• Pirie et al. (2018) Mouse genome-wide association studies and systems genetics uncover the genetic architecture associated with hepatic pharmacokinetic and pharmacodynamic properties of a constrained ethyl antisense oligonucleotide targeting Malat1. PLoS Genet. 14:e1007732
  PMID: 30372444
• Rath et al. (2018) Rho Kinase Inhibition by AT13148 Blocks Pancreatic Ductal Adenocarcinoma Invasion and Tumor Growth. Cancer Res. 78:3321
  PMID: 29669760
• Ford et al. (2018) A Cell/Cilia Cycle Biosensor for Single-Cell Kinetics Reveals Persistence of Cilia after G1/S Transition Is a General Property in Cells and Mice. Dev Cell. 47:509
  PMID: 30458140
• Sheng et al. (2018) A stably self-renewing adult blood-derived induced neural stem cell exhibiting patternability and epigenetic rejuvenation. Nat Commun. 9:4047
  PMID: 30279449
• Ackermann et al. (2018) Bioreactor-based mass production of human iPSC-derived macrophages enables immunotherapies against bacterial airway infections. Nat Commun. 9:5088
  PMID: 30504915
• Pitha et al. (2018) Rho-Kinase Inhibition Reduces Myofibroblast Differentiation and Proliferation of Scleral Fibroblasts Induced by Transforming Growth Factor β and Experimental Glaucoma. Transl Vis Sci Technol. 7:6
  PMID: 30479877
• Schaffer et al. (2018) PKCε Inhibits Neuronal Dendritic Spine Development through Dual Phosphorylation of Ephexin5. Cell Rep. 25:2470
  PMID: 30485813
• Fazakas et al. (2018) Rho-Kinase Inhibition Ameliorates D.nib-Induced Endothelial Dysfunction and Pulmonary Hypertension. Front Physiol. 9:537
  PMID: 29867576
• Ronaldson-Bouchard et al. (2018) Advanced maturation of human cardiac tissue grown from pluripotent stem cells. Nature. 556:239
  PMID: 29618819
• Sharma et al. (2018) Human Induced Pluripotent Stem Cell Production and Expansion from Blood using a Non-Integrating Viral Reprogramming Vector. Curr Protoc Mol Biol. 122:e58
  PMID: 29851250
• Sharma et al. (2018) Use of human induced pluripotent stem cell-derived cardiomyocytes to assess drug cardiotoxicity. Nat Protoc. 13:3018
  PMID: 30413796
• Mehta et al. (2018) Human Huntington's Disease iPSC-Derived Cortical Neurons Display Altered Transcriptomics, Morphology, and Maturation. Cell Rep. 25:1081
  PMID: 30355486
• Lynch et al. (2018) Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium. Cell Stem Cell. 22:653
  PMID: 29656941
• Gupta et al. (2018) CRISPR/Cas9-based Targeted Genome Editing for the Development of Monogenic Diseases Models with Human Pluripotent Stem Cells. Curr Protoc Stem Cell Biol. 45:e50
  PMID: 30040245
• McCauley et al. (2018) Derivation of Epithelial-Only Airway Organoids from Human Pluripotent Stem Cells. Curr Protoc Stem Cell Biol. 45:e51
  PMID: 30040246
• Asumda et al. (2018) Differentiation of hepatocyte-like cells from human pluripotent stem cells using small molecules. Differentiation. 101:16
  PMID: 29626713
• Benedicto (2017) Concerted regulation of retinal pigment epithelium basement membrane and barrier function by angiocrine factors. Nat Commun. 8:15374
  PMID: 28524846
• Xi (2017) In Vivo Human Somitogenesis Guides Somite Development from hPSCs. Cell Rep. 18(6):1573
  PMID: 28178531
• Hall (2017) Mesoderm-specific Stat3 deletion affects expression of Sox9 yielding Sox9-dependent phenotypes. PLoS Genet. 13(2):e1006610
  PMID: 28166224
• Kotton et al. (2017) Differentiation of human pluripotent stem cells into functional lung alveolar epithelial cells. Cell Stem Cell.. 21:472
  PMID: 28965766
• Tchieu et al. (2017) A modular platform for differentiation of human PSCs into all major ectodermal lineages. Cell Stem Cell.. 31:399
  PMID: 28886367
• Shi (2017) The novel cannabinoid receptor GPR55 mediates anxiolytic-like effects in the medial orbital cortex of mice with acute stress. Mol Brain. 10(1):38
  PMID: 28800762
• Shao (2017) A pluripotent stem cell-based model for post-implantation human amniotic sac development. Nat Commun. 8(1):208
  PMID: 28785084
• Bonan et al. (2017) Membrane-bound ICAM-1 contributes to the onset of proinvasive tumor stroma by controlling acto-myosin contractility in carcinoma-associated fibroblasts. Oncotarget. 8:1304
  PMID: 27901489
• Subramanian et al. (2017) Dynamic behaviour of human neuroepithelial cells in the developing forebrain. Nat Commun. 8:14167
  PMID: 28139695
• Lee et al. (2017) Human Pluripotent Stem Cell-Derived Atrial and Ventricular Cardiomyocytes Develop from Distinct Mesoderm Populations. Cell Stem Cell. 21:179
  PMID: 28777944
• Rath et al. (2017) ROCK signaling promotes collagen remodeling to facilitate invasive pancreatic ductal adenocarcinoma tumor cell growth. EMBO Mol Med. 9:198
  PMID: 28031255
• Hamann et al. (2017) Entosis Is Induced by Glucose Starvation. Cell Rep. 20:201
  PMID: 28683313
• Aguisanda et al. (2017) Neural stem cells for disease modeling of Wolman disease and evaluation of therapeutics. Orphanet J Rare Dis. 12:120
  PMID: 28659158
• Ferland et al. (2017) Chemerin-induced arterial contraction is Gi- and calcium-dependent. Vascul Pharmacol. 88:30
  PMID: 27890480
• Mohapatra et al. (2017) An essential role of CBL and CBL-B ubiquitin ligases in mammary stem cell maintenance. Development. 144:1072
  PMID: 28100467
• Tischfield et al. (2017) Atypical PKC and Notch Inhibition Differentially Modulate Cortical Interneuron Subclass Fate from Embryonic Stem Cells. Stem Cell Reports. 8:1135
  PMID: 28416285
• Yang et al. (2017) Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 169:243
  PMID: 28388409
• Abud et al. (2017) iPSC-Derived Human Microglia-like Cells to Study Neurological Diseases. Neuron. 94:278
  PMID: 28426964
• Wang et al. (2017) Single-cell gene expression analysis reveals regulators of distinct cell subpopulations among developing human neurons. Genome Res. 27:1783
  PMID: 29030469
• McCauley et al. (2017) Efficient Derivation of Functional Human Airway Epithelium from Pluripotent Stem Cells via Temporal Regulation of Wnt Signaling. Cell Stem Cell. 20:844
  PMID: 28366587
• Morizane and Bonventre (2017) Generation of nephron progenitor cells and kidney organoids from human pluripotent stem cells. Nat Protoc. 12:195
  PMID: 28005067
• Kinarivala et al. (2017) Discovery of Aromatic Carbamates that Confer Neuroprotective Activity by Enhancing Autophagy and Inducing the Anti-Apoptotic Protein B-Cell Lymphoma 2 (Bcl-2). J Med Chem. 60:9739
  PMID: 29110485
• Bershteyn et al. (2017) Human iPSC-Derived Cerebral Organoids Model Cellular Features of Lissencephaly and Reveal Prolonged Mitosis of Outer Radial Glia. Cell Stem Cell. 20:435
  PMID: 28111201
• Bao et al. (2017) Directed differentiation and long-term maintenance of epicardial cells derived from human pluripotent stem cells under fully defined conditions. Nat Protoc. 12:1890
  PMID: 28817124
• Vermilyea et al. (2017) Induced Pluripotent Stem Cell-Derived Dopaminergic Neurons from Adult Common Marmoset Fibroblasts. Stem Cells Dev. 26:1225
  PMID: 28635509
• Sloan et al. (2017) Human Astrocyte Maturation Captured in 3D Cerebral Cortical Spheroids Derived from Pluripotent Stem Cells. Neuron. 95:779
  PMID: 28817799
• Major et al. (2017) Derivation of telencephalic oligodendrocyte progenitors from human pluripotent stem cells. Curr Protoc Stem Cell Biol. 39:1H.10.1
  PMID: 29081882
• Shukla et al. (2017) ASXL3 Is a Novel Pluripotency Factor in Human Respiratory Epithelial Cells and a Potential Therapeutic Target in Small Cell Lung Cancer. Cancer Res. 77:6267
  PMID: 28935813
• Hubaud et al. (2017) Excitable Dynamics and Yap-Dependent Mechanical Cues Drive the Segmentation Clock. Cell. 171:668
  PMID: 28942924
• Edwards et al. (2017) The receptor tyrosine kinase EphA2 promotes glutamine metabolism in tumors by activating the transcriptional coactivators YAP and TAZ. Sci Signal. 10
  PMID: 29208682
• Mou et al. (2016) Dual SMAD Signaling Inhibition Enables Long-Term Expansion of Diverse Epithelial Basal Cells Cell: Stem Cell. 19:217
  PMID: 27320041
• Foulke-Abel et al. (2016) Human Enteroids as a Model of Upper Small Intestinal Ion Transport Physiology and Pathophysiology. Nat Commun. 150:638
  PMID: 26677983
• Guye et al. (2016) Genetically engineering self-organization of human pluripotent stem cells into a liver bud-like tissue using Gata6. Sci Rep. 7:10243
  PMID: 26732624
• Balcioglu et al. (2016) Tumor-induced remote ECM network orientation steers angiogenesis. Development. 6:22580
  PMID: 26931404
• Borgs et al. (2016) DArgic neurons differentiating from LRRK2 G2019S induced pluripotent stem cells show early neuritic branching defects. Scientific Reports. 6:33377
  PMID: 27640816
• Chal et al. (2016) Generation of human muscle fibers and satellite-like cells from human pluripotent stem cells in vitro. Nat.Protoc.. 11:1833
  PMID: 27583644
• Jardé et al. (2016) Wnt and Neuregulin1/ErbB signalling extends 3D culture of hormone responsive mammary organoids Nature Communications. 7:13207
  PMID: 27782124
• Palpant et al. (2016) Generating high-purity cardiac and endothelial derivatives from patterned mesoderm using humanpluripotent stem cells. Nature Protocols. 12:15
  PMID: 27906170
• Kellner et al. (2016) Nogo-A controls structural plasticity at dendritic spines by rapidly modulating actin dynamics. Hippocampus. 6:816
  PMID: 26748478
• Yu and Fernandez-Gonzalez (2016) Local mechanical forces promote polarized junctional assembly and axis elongation in Drosophila. Elife. 5
  PMID: 26747941
• Koopmans et al. (2016) Regulation of actin dynamics by WNT-5A: implications for human airway smooth muscle contraction. Sci Rep. 6:30676
  PMID: 27468699
• Manno et al. (2016) Molecular Diversity of Midbrain Development in Mouse, Human, and Stem Cells. Cell. 167:566
  PMID: 27716510
• Rath et al. (2016) ROCK signalling induced gene expression changes in mouse pancreatic ductal adenocarcinoma cells. Sci Data. 3:160101
  PMID: 27824338
• Hien et al. (2016) Elevated Glucose Levels Promote Contractile and Cytoskeletal Gene Expression in Vascular Smooth Muscle via Rho/Protein Kinase C and Actin Polymerization. J Biol Chem. 291:3552
  PMID: 26683376
• Pei et al. (2016) Risk of prenatal depression and stress treatment: alteration on serotonin system of offspring through exposure to Fluox.. Sci Rep. 6:33822
  PMID: 27703173
• Mulay et al. (2016) An in vitro model of murine middle ear epithelium. Dis Model Mech. 9:1405
  PMID: 27660200
• Stebbins et al. (2016) Differentiation and characterization of human pluripotent stem cell-derived brain microvascular endothelial cells. Methods. 101:93
  PMID: 26518252
• Zeltner et al. (2016) Capturing the biology of disease severity in a PSC-based model of familial dysautonomia. Nat Med. 22:1421
  PMID: 27841875
• Long et al. (2016) Induced Pluripotent Stem Cells for Disease Modeling and Evaluation of Therapeutics for Niemann-Pick Disease Type A. Stem Cells Transl Med. 5:1644
  PMID: 27484861
• Wilson et al. (2016) Cryopreservation of Brain Endothelial Cells Derived from Human Induced Pluripotent Stem Cells Is Enhanced by Rho-Associated Coiled Coil-Containing Kinase Inhibition. Tissue Eng Part C Methods. 22:1085
  PMID: 27846787
• Tidball et al. (2016) Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human Induced Pluripotent Stem Cells. PLoS One. 11:e0150372
  PMID: 26982737
• Davies et al. (2015) The Viral Mimetic Polyinosinic:Polycytidylic Acid Alters the Growth Characteristics of Small Intestinal and Colonic Crypt Cultures. PLoS One. 10:e0138531
  PMID: 26414184
• Madsen et al. (2015) Hypoxia and loss of PHD2 inactivate stromal fibroblasts to decrease tumour stiffness and metastasis. EMBO Rep. 16:1394
  PMID: 26323721
• Chen et al. (2015) Variations in Glycogen Synthesis in Human Pluripotent Stem Cells with Altered Pluripotent States. PLoS One. 10:e0142554
  PMID: 26565809
• Romero et al. (2015) A panel of induced pluripotent stem cells from chimpanzees: a resource for comparative functional genomics. Elife. 4:e07103
  PMID: 26102527
• Edri et al. (2015) Analysing human neural stem cell ontogeny by consecutive isolation of Notch active neural progenitors. Nat Commun. 6:6500
  PMID: 25799239
• Serra et al. (2015) SimV. Increases Fibulin-2 Expression in Human Coronary Artery Smooth Muscle Cells via RhoA/Rho-Kinase Signaling Pathway Inhibition. PLoS One. 10:e0133875
  PMID: 26207907
• Gjorevski et al. (2015) Dynamic tensile forces drive collective cell migration through three-dimensional extracellular matrices. Sci Rep. 5:11458
  PMID: 26165921
• Piao et al. (2015) Human embryonic stem cell-derived oligodendrocyte progenitors remyelinate the brain and rescue behavioral deficits following radiation. Cell Stem Cell. 16:198
  PMID: 25658373
• Lee et al. (2015) Machine learning plus optical flow: a simple and sensitive method to detect cardioactive drugs. Sci Rep. 5:11817
  PMID: 26139150
• Tyson et al. (2015) Duration of culture and sonic hedgehog signaling differentially specify PV versus SST cortical interneuron fates from embryonic stem cells. Stem Cells. 142:1267
  PMID: 25804737
• Balcioglu et al. (2015) The integrin expression profile modulates orientation and dynamics of force transmission at cell-matrix adhesions. Nat Biotechnol. 128:1316
  PMID: 25663698
• Morizane et al. (2015) Nephron organoids derived from human pluripotent stem cells model kidney development and injury. Nat Commun. 33:1193
  PMID: 26458176
• Chaudhuri et al. (2015) Substrate stress relaxation regulates cell spreading. Brain. 6:6364
  PMID: 25695512
• Iovino et al. (2015) Early maturation and distinct tau pathology in induced pluripotent stem cell-derived neurons from patients with MAPT mutations. Development. 138:3345
  PMID: 26220942
• Jönsson et al. (2015) Comprehensive analysis of microRNA expression in regionalized human neural progenitor cells reveals microRNA-10 as a caudalizing factor. Int J Nanomedicine. 142:3166
  PMID: 26395143
• Tai et al. (2015) SimV. enhances Rho/actin/cell rigidity pathway contributing to mesenchymal stem cells' osteogenic differentiation. Nat Commun. 10:5881
  PMID: 26451103
• Sakaguchi et al. (2015) Generation of functional hippocampal neurons from self-organizing human embryonic stem cell-derived dorsomedial telencephalic tissue. Mol Vis. 6:8896
  PMID: 26573335
• Su et al. (2015) Phenotypes of trypsin- and Col. -prepared bovine corneal endothelial cells in the presence of a selective Rho kinase inhibitor, Y-27632. PLoS Comput Biol. 21:633
  PMID: 26097378
• Ziv et al. (2015) Quantitative Live Imaging of Human Embryonic Stem Cell Derived Neural Rosettes Reveals Structure-Function Dynamics Coupled to Cortical Development. Stem Cell Reports. 11:e1004453
  PMID: 26473351
• Fernandes et al. (2015) Comparison of Human Embryonic Stem Cell-Derived Cardiomyocytes, Cardiovascular Progenitors, and Bone Marrow Mononuclear Cells for Cardiac Repair. Bone Res. NULL
  PMID: 26607951
• Maharam et al. (2015) Rho/Rock signal transduction pathway is required for MSC tenogenic differentiation. Stem Cell Res Ther. 3:15015
  PMID: 26509098
• Luzzani et al. (2015) A therapy-grade protocol for differentiation of pluripotent stem cells into mesenchymal stem cells using platelet lysate as supplement. Int J Cancer. 6:6
  PMID: 25582222
• Choi et al. (2015) SDF-1α stiffens myeloma bone marrow mesenchymal stromal cells through the activation of RhoA-ROCK-Myosin II. Stem Cell Reports. 136:E219
  PMID: 25137150
• Höfner et al. (2015) Defined conditions for the isolation and expansion of basal prostate progenitor cells of mouse and human origin. PLoS One. 4:503
  PMID: 25702639
• Härmä et al. (2015) Optimization of Invasion-Specific Effects of Betulin Derivatives on Prostate Cancer Cells through Lead Development. Stem Cell Reports. 10:e0126111
  PMID: 25965345
• Lachmann et al. (2015) Large-scale hematopoietic differentiation of human induced pluripotent stem cells provides granulocytes or macrophages for cell replacement therapies. Nat Commun. 4:282
  PMID: 25680479
• Abraham et al. (2015) A Rac/Cdc42 exchange factor complex promotes formation of lateral filopodia and blood vessel lumen morphogenesis. Stem Cell Reports. 6:7286
  PMID: 26129894
• Arbab et al. (2015) Cloning-free CRISPR. Cell. 5:908
  PMID: 26527385
• Ruprecht et al. (2015) Cortical contractility triggers a stochastic switch to fast amoeboid cell motility. Int J Mol Sci. 160:673
  PMID: 25679761
• Vergara et al. (2015) Transgenic plants as low-cost platform for chemotherapeutic drugs screening. J Biol Chem. 16:2174
  PMID: 25608652
• Lee et al. (2015) Odontogenic Ameloblast-associated Protein (ODAM) Mediates Junctional Epithelium Attachment to Teeth via Integrin-ODAM-Rho Guanine Nucleotide Exchange Factor 5 (ARHGEF5)-RhoA Signaling. Toxicol Sci. 290:14740
  PMID: 25911094
• Pattabiraman et al. (2015) RhoA GTPase-induced ocular hypertension in a rodent model is associated with increased fibrogenic activity in the trabecular meshwork. Autophagy. 185:496
  PMID: 25499974
• Rempel et al. (2015) A transcriptome-based classifier to identify developmental toxicants by stem cell testing: design, validation and optimization for histone deacetylase inhibitors. Arch Toxicol. 89:1599
  PMID: 26272509
• Sun et al. (2014) Competition between human cells by entosis. Cell Res. 24:1299
  PMID: 25342560
• Sun et al. (2014) Induction of entosis by epithelial cadherin expression. Cell Res. 24:1288
  PMID: 25342558
• Pavlov et al. (2014) Role of Rho GDP dissociation inhibitor α in control of epithelial sodium channel (ENaC)-mediated sodium reabsorption. J Biol Chem. 289:28651
  PMID: 25164814
• Wile et al. (2014) Molecular beacon-enabled purification of living cells by targeting cell type-specific mRNAs. Nat Protoc. 9:2411
  PMID: 25232937
• Mich et al. (2014) Prospective identification of functionally distinct stem cells and neurosphere-initiating cells in adult mouse forebrain. Elife. 3:e02669
  PMID: 24843006
• Liu and Chen (2014) Cryopreservation of human pluripotent stem cells in defined medium. Curr Protoc Stem Cell Biol. 31:1C.17.1
  PMID: 25366897
• Luo et al. (2014) Generation of GFP Reporter Human Induced Pluripotent Stem Cells Using AAVS1 Safe Harbor Transcription Activator-Like Effector Nuclease. Curr Protoc Stem Cell Biol. 29:5A.7.1
  PMID: 24838915
• Huang et al. (2014) Efficient generation of lung and airway epithelial cells from human pluripotent stem cells. Nat Biotechnol. 32:84
  PMID: 24291815
• Williams et al. (2014) An in vivo role for Rho kinase activation in the tumour vascular disrupting activity of combretastatin A-4 3-O-phosphate. Br J Pharmacol. 171:4902
  PMID: 24930520
• McNary et al. (2014) Transforming growth factor β-induced superficial zone protein accumulation in the surface zone of articular cartilage is dependent on the cytoskeleton. Tissue Eng Part A. 20:921
  PMID: 24116978
• Keimpema et al. (2014) GABAergic terminals are a source of galanin to modulate cholinergic neuron development in the neonatal forebrain. Cereb Cortex. 24:3277
  PMID: 23897649
• Moon et al. (2014) Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis. Mucosal Immunol. 7:818
  PMID: 24220295
• Orgaz et al. (2014) Diverse matrix metalloproteinase functions regulate cancer amoeboid migration. Nat Commun. 5:4255
  PMID: 24963846
• Wrighton et al. (2014) Signals from the surface modulate differentiation of human pluripotent stem cells through glycosaminoglycans and integrins. Circ Res. 111:18126
  PMID: 25422477
• Shelton et al. (2014) Derivation and expansion of PAX7-positive muscle progenitors from human and mouse embryonic stem cells. Stem Cell Reports. 3:516
  PMID: 25241748
• Kameoka et al. (2014) A high-throughput screen for teratogens using human pluripotent stem cells. J Biomol Screen. 137:76
  PMID: 24154490
• Aubdool et al. (2014) TRPA1 is essential for the vascular response to environmental cold exposure. Korean J Physiol Pharmacol. 5:5732
  PMID: 25501034
• Kirschstein et al. (2014) Age-dependent contribution of Rho kinase in CB-induced contraction of human detrusor smooth muscle in vitro. Acta Pharmacol Sin. 35:74
  PMID: 24122009
• Dickover et al. (2014) The atypical Rho GTPase, RhoU, regulates cell-adhesion molecules during cardiac morphogenesis. Dev Biol. 389:182
  PMID: 24607366
• Cossette et al. (2014) Sucrose non-fermenting related kinase enzyme is essential for cardiac metabolism. Biol Open. 4:48
  PMID: 25505152
• Feng et al. (2014) Hippo-independent activation of YAP by the GNAQ uveal melanoma oncogene through a trio-regulated rho GTPase signaling circuitry. Cancer Cell. 25:831
  PMID: 24882515
• Kirkeby et al. (2013) Generating regionalized neuronal cells from pluripotency, a step-by-step protocol. Front Cell Neurosci. 6:64
  PMID: 23316134
• Smith et al. (2013) Interleukin-6 and oncostatin-M synergize with the PI3K/AKT pathway to promote aggressive prostate malignancy in mouse and human tissues. Mol Cancer Res. 11:1159
  PMID: 23867565
• Calvo et al. (2013) Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts. Nat Cell Biol. 15:637
  PMID: 23708000
• Zeller et al. (2013) The role of mechanical force and ROS in integrin-dependent signals. PLoS One. 8:e64897
  PMID: 23738008
• Krajcovic et al. (2013) mTOR regulates phagosome and entotic vacuole fission. Mol Biol Cell. 24:3736
  PMID: 24088573
• Barthwal et al. (2013) Fluid-phase pinocytosis of native low density lipoprotein promotes murine M-CSF differentiated macrophage foam cell formation. PLoS One. 8:e58054
  PMID: 23536783
• Hutchins et al. (2013) Calcium release-dependent actin flow in the leading process mediates axophilic migration. J Cell Biochem. 33:11361
  PMID: 23843509
• Lazzeroni et al. (2013) A phenotypic screening assay for modulators of huntingtin-induced transcriptional dysregulation. Exp Neurol. 18:984
  PMID: 23562876
• Pol et al. (2013) Sox10-MCS5 enhancer dynamically tracks human oligodendrocyte progenitor fate. Stem Cell Res. 247:694
  PMID: 23507034
• Crompton et al. (2013) Stepwise, non-adherent differentiation of human pluripotent stem cells to generate basal forebrain cholinergic neurons via hedgehog signaling. Nat Cell Biol. 11:1206
  PMID: 24013066
• Lin et al. (2013) Activation of β 1 but not β 3 integrin increases cell traction forces. J Neurosci. 587:763
  PMID: 23395612
• Lu et al. (2013) Generation of integration-free and region-specific neural progenitors from primate fibroblasts. Curr Biol. 3:1580
  PMID: 23643533
• Hannan et al. (2013) Inhibition of Rho-kinase improves erectile function, increases nitric oxide signaling and decreases penile apoptosis in a rat model of cavernous nerve injury. Am J Physiol Lung Cell Mol Physiol. 189:1155
  PMID: 23021998
• Zhu and Nelson (2013) PI3K regulates branch initiation and extension of cultured mammary epithelia via Akt and Rac1 respectively. Cell. 379:235
  PMID: 23665174
• Li et al. (2013) Shaping organs by a wingless-int/Notch/nonmuscle myosin module which orients feather bud elongation. Proc Natl Acad Sci U S A. 110:E1452
  PMID: 23576731
• Matsumoto et al. (2013) Induced pluripotent stem cells from patients with human fibrodysplasia ossificans progressiva show increased mineralization and cartilage formation. Orphanet J Rare Dis. 8:190
  PMID: 24321451
• Lian et al. (2013) Directed cardiomyocyte differentiation from human pluripotent stem cells by modulating Wnt/β-catenin signaling under fully defined conditions. Nat Protoc. 8:162
  PMID: 23257984
• Goldspink et al. (2013) The microtubule end-binding protein EB2 is a central regulator of microtubule reorganisation in apico-basal epithelial differentiation. J Cell Sci. 126:4000
  PMID: 23813963
• Lazzeroni et al. (2013) A phenotypic screening assay for modulators of huntingtin-induced transcriptional dysregulation J Biomol Screen. 18:984
  PMID: 23562876
• Beers et al. (2012) Passaging and colony expansion of human pluripotent stem cells by enzyme-free dissociation in chemically defined culture conditions. Nat Protoc. 7:2029
  PMID: 23099485
• Harel et al. (2012) ZFX controls the self-renewal of human embryonic stem cells. PLoS One. 7:e42302
  PMID: 22879936
• Paige et al. (2012) A temporal chromatin signature in human embryonic stem cells identifies regulators of cardiac development. Cell. 151:221
  PMID: 22981225
• Roller et al. (2012) Synthetic lethal screening with small-molecule inhibitors provides a pathway to rational combination therapies for melanoma. Mol Cancer Ther. 11:2505
  PMID: 22962324
• Neely et al. (2012) DMH1, a highly selective small molecule BMP inhibitor promotes neurogenesis of hiPSCs: comparison of PAX6 and SOX1 expression during neural induction. Proc Natl Acad Sci U S A. 3:482
  PMID: 22860217
• Guo et al. (2012) Slug and Sox9 cooperatively determine the mammary stem cell state. J Cell Sci. 148:1015
  PMID: 22385965
• Walker et al. (2012) Intra-axonal translation of RhoA promotes axon growth inhibition by CSPG. J Cell Sci. 32:14442
  PMID: 23055514
• Goulopoulou et al. (2012) Pregnancy reduces RhoA/Rho kinase and protein kinase C signaling pathways downstream of thromboxane receptor activation in the rat uterine artery. Am J Physiol Heart Circ Physiol. 302:H2477
  PMID: 22542618
• Gupta et al. (2012) Soluble epoxide hydrolase: sex differences and role in endothelial cell survival. Arterioscler Thromb Vasc Biol. 32:1936
  PMID: 22723436
• Loubet et al. (2012) Neuritogenesis: the prion protein controls β1 integrin signaling activity. FASEB J. 26:678
  PMID: 22038049
• Sherwood et al. (2011) Wnt signaling specifies and patterns intestinal endoderm. Mech Dev. 128:387
  PMID: 21854845
• Kaur et al. (2011) RhoJ/TCL regulates endothelial motility and tube formation and modulates actomyosin contractility and focal adhesion numbers. Arterioscler Thromb Vasc Biol. 31:657
  PMID: 21148427
• Abreu-Blanco et al. (2011) Cell wound repair in Drosophila occurs through three distinct phases of membrane and cytoskeletal remodeling. J Cell Biol. 193:455
  PMID: 21518790
• Lee et al. (2011) The Relaxing Effect of α-Defensin 1 on the Adrenergic Responses of Rat Bladder. Dev Biol. 15:143
  PMID: 21860592
• Vallenius et al. (2011) An association between NUAK2 and MRIP reveals a novel mechanism for regulation of actin stress fibers. Integr Biol (Camb). 124:384
  PMID: 21242312
• Stiegler et al. (2011) Assessment of chemical-induced impairment of human neurite outgrowth by multiparametric live cell imaging in high-density cultures. Toxicol Sci. 121:73
  PMID: 21342877
• Yang et al. (2011) Measurement and analysis of traction force dynamics in response to vasoactive agonists. Integr Biol (Camb). 3:663
  PMID: 21445393
• Díez et al. (2010) STAT inhibit angiotensin II/Smad pathway and related vascular fibrosis, by a TGF-β-independent process. PLoS One. 5:e14145
  PMID: 21152444
• Gomez et al. (2010) Tissue geometry patterns epithelial-mesenchymal transition via intercellular mechanotransduction. ACS Chem Neurosci. 110:44
  PMID: 20336666
• Kim et al. (2010) PDGF signaling is required for epicardial function and blood vessel formation in regenerating zebrafish hearts. FEBS Lett. 107:17206
  PMID: 20858732
• Cao et al. (2010) Cortical actin dynamics facilitate early-stage centrosome separation. J Pharmacol Exp Ther. 20:770
  PMID: 20409712
• Gjorevski and Nelson (2010) Endogenous patterns of mechanical stress are required for branching morphogenesis. Stroke. 2:424
  PMID: 20717570
• Simões et al. (2010) Rho-kinase directs Bazooka/Par-3 planar polarity during Drosophila axis elongation. Dev Cell. 19:377
  PMID: 20833361
• Giampieri et al. (2009) Localized and reversible TGFβ signalling switches breast cancer cells from cohesive to single cell motility. Nat Commun. 11:1287
  PMID: 19838175
• Desai et al. (2009) Cell polarity triggered by cell-cell adhesion via E-cadherin. Br J Pharmacol. 122:905
  PMID: 19258396
• Silva-Santos et al. (2009) The Rho-A/Rho-kinase pathway is up-regulated but remains inhibited by cyclic guanosine monophosphate-dependent mechanisms during endotoxemia in small mesenteric arteries. J Biol Chem. 37:1716
  PMID: 19325475
• Rodríguez-Vita et al. (2008) Essential role of TGF-beta/Smad pathway on statin dependent vascular smooth muscle cell regulation. PLoS One. 3:e3959
  PMID: 19088845
• Ruiz and Chen (2008) Emergence of patterned stem cell differentiation within multicellular structures. J Cell Sci. 26:2921
  PMID: 18703661
• Inan and Büyükafşar (2008) Antiepileptic effects of two Rho-kinase inhibitors, Y-27632 and fasudil, in mice. Am J Pathol. 155:44
  PMID: 18536751
• Schaafsma et al. (2007) Ins induces airway smooth muscle contraction. Cell Rep. 150:136
  PMID: 17160007
• Bhadriraju et al. (2007) Quantifying myosin light chain phosphorylation in single adherent cells with automated fluorescence microscopy. J Biol Chem. 8:43
  PMID: 17941977
• Wyckoff et al. (2006) ROCK- and myosin-dependent matrix deformation enables protease-independent tumor-cell invasion in vivo. Curr Biol. 16:1515
  PMID: 16890527
• Guillemot and Citi (2006) Cingulin regulates claudin-2 expression and cell proliferation through the small GTPase RhoA. Mol Biol Cell. 17:3569
  PMID: 16723500
• Muñoz-García et al. (2006) Fn14 is upregulated in cytokine-stimulated vascular smooth muscle cells and is expressed in human carotid atherosclerotic plaques: modulation by AtoVas. Proc Natl Acad Sci U S A. 37:2044
  PMID: 16809572
• Rajnicek et al. (2006) Temporally and spatially coordinated roles for Rho, Rac, Cdc42 and their effectors in growth cone guidance by a physiological electric field. J Cell Sci. 119:1723
  PMID: 16595546
• Hartmann et al. (2005) CXCR4 chemokine receptor and integrin signaling co-operate in mediating adhesion and chemoresistance in small cell lung cancer (SCLC) cells. Oncogene. 24:4462
  PMID: 15806155
• Rodríguez-Vita et al. (2005) Endothelin-1, via ETA receptor and independently of transforming growth factor-β, increases the connective tissue growth factor in vascular smooth muscle cells. Am J Physiol Cell Physiol. 97:125
  PMID: 15976312
• Turner et al. (2004) The activity of the plexin-A1 receptor is regulated by Rac. J Biol Chem. 279:33199
  PMID: 15187088
• Schneider et al. (2004) Signal transduction underlying CB-induced contraction of human urinary bladder. J Biol Chem. 309:1148
  PMID: 14769832
• Prahalad et al. (2004) Regulation of MDCK cell-substratum adhesion by RhoA and myosin light chain kinase after ATP depletion. Am J Physiol Cell Physiol. 286:C693
  PMID: 14644769
• Fleichman et al. (2004) Signal transduction underlying CB-induced contraction of rat urinary bladder. II. Protein kinases. J Pharmacol Exp Ther. 308:54
  PMID: 14532355
• Surks et al. (2003) Myosin phosphatase-Rho interacting protein. A new member of the myosin phosphatase complex that directly binds RhoA. J Biol Chem. 278:51484
  PMID: 14506264
• Altmann et al. (2003) Comparison of signalling mechanisms involved in rat mesenteric microvessel contraction by noradrenaline and sphingosylphosphorylcholine. Br J Pharmacol. 138:261
  PMID: 12522098
• Wibberley et al. (2003) Expression and functional role of Rho-kinase in rat urinary bladder smooth muscle. Br J Pharmacol. 138:757
  PMID: 12642376
• Roovers and Assoian (2003) Effects of rho kinase and actin stress fibers on sustained extracellular signal-regulated kinase activity and activation of G(1) phase cyclin-dependent kinases. Mol Cell Biol. 23:4283
  PMID: 12773570
• An et al. (2002) Stiffness changes in cultured airway smooth muscle cells. Gastroenterology. 283:C792
  PMID: 12176736
• Hippenstiel et al. (2002) Rho protein inactivation induced apoptosis of cultured human endothelial cells. BMC Cell Biol. 283:L830
  PMID: 12225960
• Huang et al. (2002) Differential regulation of cell migration, actin stress fiber organization, and cell transformation by functional domains of Crk-associated substrate. Crit Care Med. 277:27265
  PMID: 12011056
• Jung et al. (2002) Interaction of cofilin with triose-phosphate isomerase contributes glycolytic fuel for Na,K-ATPase via Rho-mediated signaling pathway. Br J Pharmacol. 277:48931
  PMID: 12359716
• Vinson et al. (2001) Myelin-associated glycoprotein interacts with ganglioside GT1b. A mechanism for neurite outgrowth inhibition. J Urol. 276:20280
  PMID: 11279053

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• Consistent performance

  Name: Ted Mason
  Species: Human
  Assay Type: In Vitro
  ROCKi has consistently performed in iPSC cell culture work. Well packaged vials are resuspended and aliquoted for -20 storage. Cells passaged or fed with ROCKi media have shown good viability. This is a regular purchase for the labs at a reasonable price.Images @10x magnification show limited differentiation of iPSCs after 3 days in culture.
  

• Excellent product

  Name: Jack Schnell
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: iPSCs
  We add this product at a concentration of 10 uM to promote cell survival in in vitro iPSC cultures.
  Easy to manage and works as expected
  

• ROCK Inhibitor

  Name: Anonymous
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: Organoids
  To generate human intestinal organoids
  PMID: 31306552 Reference

• test

  Name: Veselina Petrova
  Species: Human
  Assay Type: In Vitro
  I used this product on freshly split and plate human iPSC cells to help cell survival and adherence. I used the product at 10 mM concentration which I diluted in 1:1000 in culture media and left the cells at 37C, 5% CO2 for 24 hours before replacing with fresh culture media.

• For hPSC culture

  Name: Anonymous
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: Human PSC
  For hPSC culture, final concentration 10mM. Reconstitute 10 mg of Y27632 in 3.0792 ml of PBS. Make 100µl aliquots and keep them at −20 °C for up to 6 months.
  PMID: PMID, 27841875
  

• Worked great and at a great price

  Name: Tres Davis
  Species: Mouse
  Assay Type: Ex Vivo
  HPLC

• Neural Induction Conditions

  Name: Anonymous
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: H9
  ROCK inhibitor Y-27632 (10 mM)
  PMID: 30656621
  

• Great for passaging stem cells.

  Name: Samiha Shaikh
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: iPSC
  Great for passaging huiPSCs with dissociation into single cells.
  

• Great for single iPS cell survival

  Name: Anonymous
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: iPSC
  Used during single cell passage for CRISPR clone isolation, works well and no difference found between multiple batches. Cells show characteristic 'spiky' morphology upon addition to the medium.
  I use at 1:1000 and store at -20C. I remove the compound from medium 24 hours after plating.
  

• For iPSC culture

  Name: Pinyuan Tian
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: iPSC
  For iPSC culture, final concentration 10mM. Reconstitute 10 mg of Y27632 in 3.0792 ml of PBS.
  Make 100µl aliquots and keep them at −20 °C for up to 6 months.
  

• ROCK Inhibitor to improve cartilage integrity

  Name: Anonymous
  Species: Other
  Assay Type: In Vitro
  Cell Line/Tissue: chondrocyte
  I dissolved in DMSO
  

• I prepare 20mg of the product in 5.88mL H2O and I use 1uL/mL of the stock in my cell culture after the cell splitting

  Name: Anonymous
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: human foreskin fibroblasts-derived-IPS
  I used it in two human IPS cell lines, 5uM concentration the first 24 h after the splitting. The use of this reagent improves substantially the cell survival.
  Keep the stock frozen at -20°C. I use it freshly added to the medium when splitting the cells.
  

• ROCK Inhibitor to improve cell survival

  Name: Hudson DE OLIVEIRA BEZERRA
  Species: Human
  Assay Type: In Vitro
  Cell Line/Tissue: H1 (W01)
  My team uses this product to improve human embryonic stem cells survival in single cell passage methods in siRNA and CRISPR experiments. In general, we use the concentration of 10 uM. The products work very well, better than others available in the market.
  

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